Hospital and Drugmaker Move to Build Vast Database of New Yorkers’ DNA

Patients will be asked if their genetic sequence can be added to a database — shared with a pharmaceutical company — in a quest to cure a multitude of diseases.

#dna-deoxyribonucleic-acid, #genetics-and-heredity, #hospitals, #mount-sinai-medical-center, #new-york-city, #regeneron-pharmaceuticals-inc, #research

The Quest by Circadian Medicine to Make the Most of Our Body Clocks

Researchers are trying to figure out the right hour of the day to do everything. Can their studies sync us up with better health?

#biorhythms, #drugs-pharmaceuticals, #genetics-and-heredity, #hospitals, #preventive-medicine, #sleep

A Canine Companion So Nice It (Maybe) Evolved Twice

Two different ancient wolf populations contributed DNA to modern dogs, according to a new study.

#dogs, #endangered-and-extinct-species, #genetics-and-heredity, #pets, #research, #wolves, #your-feed-animals, #your-feed-science

CRISPR, 10 Years On: Learning to Rewrite the Code of Life

The gene-editing technology has led to innovations in medicine, evolution and agriculture — and raised profound ethical questions about altering human DNA.

#biology-and-biochemistry, #broad-institute, #clinical-trials, #crispr-dna, #dna-deoxyribonucleic-acid, #doudna-jennifer-a, #ethics-and-official-misconduct, #genetic-engineering, #genetics-and-heredity, #he-jiankui, #nobel-prizes, #science-and-technology, #university-of-california, #your-feed-health, #your-feed-science

We Are Political Animals. So How Much Do Genes Matter?

They’re not everything, but they’re not nothing either.

#conservatism-us-politics, #genetics-and-heredity, #liberalism-us-politics, #polls-and-public-opinion, #united-states-politics-and-government

The World’s Largest Plant Is a Self-Cloning Sea Grass in Australia

The species is called Poseidon’s ribbon weed, and researchers say it has spread to cover an area the size of Cincinnati over the past 4,500 years.

#australia, #cloning, #fish-and-other-marine-life, #flowers-and-plants, #genetics-and-heredity, #grass, #proceedings-of-the-royal-society-b-journal, #research, #your-feed-science

Australia Wields a New DNA Tool to Crack Missing-Person Mysteries

The technique can predict a person’s ancestry and physical traits without the need for a match with an existing sample in a database.

#australia, #dna-deoxyribonucleic-acid, #forensic-science, #genetics-and-heredity

Targeting the Uneven Burden of Kidney Disease on Black Americans

New treatments aim for a gene variant causing the illness in people of sub-Saharan African descent. Some experts worry that focus will neglect other factors.

#black-people, #discrimination, #drugs-pharmaceuticals, #genetics-and-heredity, #kidneys, #north-carolina, #research, #sickle-cell-anemia, #sleeping-sickness, #tests-medical

Mushrooms Took a Deadly Toxin From a Mysterious Source

Instead of evolving to produce poison, some distantly related fungi became toxic through a process called horizontal gene transfer, scientists say.

#endangered-and-extinct-species, #fungi, #genetics-and-heredity, #hazardous-and-toxic-substances, #proceedings-of-the-national-academy-of-sciences, #research, #your-feed-science

The Vanishing Variants: Lessons from Gamma, Iota and Mu

Studying the coronavirus variants that have faded away could help us prepare for what comes next, scientists say.

#colombia, #coronavirus-2019-ncov, #coronavirus-delta-variant, #coronavirus-omicron-variant, #genetics-and-heredity, #gisaid-nonprofit, #south-america, #your-feed-health, #your-feed-science

They’re All Good Dogs, and It Has Nothing to Do With Their Breed

Retrievers that don’t retrieve and Papillons that point are all possible because the genes that shape dog behavior predate modern breeding that focuses on appearance, researchers find.

#animal-behavior, #breeding-of-animals, #dogs, #genetics-and-heredity, #pets, #research, #science-journal

F.D.A. Warns Patients About Some Prenatal Genetic Tests

The agency cites concerns that some manufacturers’ claims about test performance “may not be supported with sound scientific evidence.”

#babies-and-infants, #food-and-drug-administration, #genetics-and-heredity, #pregnancy-and-childbirth, #prenatal-testing

Study Raises Questions About Popular Genetic Test for ‘Abnormal’ Embryos

The test leads people undergoing in vitro fertilization to discard thousands of embryos each year. The new research found implanting some “abnormal” embryos resulted in healthy live births.

#center-for-human-reproduction, #chromosomes, #embryos-human, #genetics-and-heredity, #gleicher-norbert, #in-vitro-fertilization, #infertility, #research, #your-feed-healthcare

Body Found in Indiana Is Identified After 30 Years

Advances in DNA technology helped the authorities to identify remains found near a highway in 1992 as those of Margaret Ann Sniegowski Jr., who had disappeared from her home in Ohio.

#dna-deoxyribonucleic-acid, #forensic-science, #genealogy, #genetics-and-heredity, #indiana, #sniegowski-margaret-ann-jr, #toledo-ohio

New DNA Analysis Supports an Unrecognized Tribe’s Ancient Roots in California

A collaboration between researchers and the Muwekma Ohlone Tribe offers new evidence that their ancestors have lived in the Bay Area for thousands of years.

#archaeology-and-anthropology, #genetics-and-heredity, #muwekma-ohlone, #native-americans, #proceedings-of-the-national-academy-of-sciences, #research, #san-francisco-bay-area-calif, #stanford-university, #university-of-illinois-urbana-champaign, #your-feed-science

‘I-65 Killer’ Who Terrorized Motel Clerks in the 1980s Is Identified

The authorities said they connected Harry Edward Greenwell, who died in 2013, to at least three murders in Kentucky and Indiana, using genetic genealogy.

#dna-deoxyribonucleic-acid, #forensic-science, #genealogy, #genetics-and-heredity, #greenwell-harry-edward, #indiana, #kentucky, #murders-attempted-murders-and-homicides, #robberies-and-thefts, #serial-murders, #sex-crimes

The Search for a Model Octopus That Won’t Die After Laying Its Eggs

A lab in Massachusetts may have finally found an eight-armed cephalopod that can serve as a model organism and assist scientific research.

#animal-abuse-rights-and-welfare, #animal-behavior, #animal-cognition, #brain, #genetic-engineering, #genetics-and-heredity, #laboratories-and-scientific-equipment, #marine-biological-laboratory, #octopus, #research, #your-feed-animals, #your-feed-science

Does Moderate Drinking Protect Your Heart? A Genetic Study Offers a New Answer.

By studying the relationship between gene variants and alcohol consumption, scientists found no real cardiac benefit to drinking, even modestly.

#alcoholic-beverages, #genetics-and-heredity, #heart, #jama-network-open, #research, #your-feed-health, #your-feed-science

Book Review: ‘Ancestor Trouble,’ by Maud Newton

Maud Newton’s “Ancestor Trouble” is a sweeping genealogical investigation that becomes an investigation of genealogy itself.

#ancestor-trouble-a-reckoning-and-a-reconciliation-book, #books-and-literature, #genealogy, #genetics-and-heredity, #newton-maud

Philanthropists Push Police Searches of DNA Databases

When the police can’t afford to solve cold cases, deep-pocketed donors can.

#crime-and-criminals, #crowdfunding-internet, #dna-deoxyribonucleic-acid, #forensic-science, #genealogy, #genetics-and-heredity, #gofundme, #philanthropy, #police

Life’s Preference for Symmetry Is Like ‘A New Law of Nature’

Techniques from computer science may help explain the tendency in biology for structures to repeat themselves.

#biology-and-biochemistry, #evolution-biology, #genetics-and-heredity, #proceedings-of-the-national-academy-of-sciences, #proteins, #research, #rna-ribonucleic-acid, #your-feed-animals, #your-feed-science

Why Do Some People Never Get Covid?

Two years into the pandemic, a Covid mystery remains.

#coronavirus-risks-and-safety-concerns, #genetics-and-heredity

We Need a New Language for Talking About Race

In the 18th century, “scientific” myths about race sought to divide people into separate groups. Today, new DNA science is revealing just how connected we really are.

#genealogy, #genetics-and-heredity, #race-and-ethnicity

Act of ‘Heresy’ Adds Horseshoe Crabs to Arachnid Family Tree

A team of researchers say that rather than occupying their own branch in the history of life on Earth, horseshoe crabs are in the same group as spiders and scorpions.

#evolution-biology, #fish-and-other-marine-life, #fossils, #genetics-and-heredity, #molecular-biology-and-evolution-journal, #paleontology, #research, #spiders, #your-feed-animals, #your-feed-science

A Parasitic Wasp Unmasked: One Species Is Actually 16 Species

The tiny, iridescent parasitoid wasp is the latest insect shown to be a cryptic complex of genetically distinct species.

#biodiversity, #genetics-and-heredity, #insect-systematics-and-diversity, #research, #wasps-insects, #your-feed-animals, #your-feed-science

It Helped Catch Serial Killers. Can It Stop Elephant Poachers, Too?

Scientists used a genetic investigation technique with the aim of helping turn the tide against illicit hauls of ivory and other animal parts.

#animals, #conservation-of-resources, #elephants, #forensic-science, #genetics-and-heredity, #ivory, #nature-human-behaviour-journal, #organized-crime, #research, #smuggling, #wildlife-trade-and-poaching, #your-feed-animals, #your-feed-science

Did the First Americans Arrive via Land Bridge? This Geneticist Says No.

In “Origin: A Genetic History of the Americas,” Jennifer Raff combines archaeology, genetics, linguistics and more to argue against a longstanding theory.

#archaeology-and-anthropology, #bones, #books-and-literature, #genealogy, #genetics-and-heredity, #indigenous-people, #origin-a-genetic-history-of-the-americas-book, #paleontology, #race-and-ethnicity, #raff-jennifer, #science-and-technology

Looking for Early Warning Signs of Pancreatic Cancer

Scientists are exploring whether the onset of diabetes may in some cases herald the existence of one of the most deadly of all cancers.

#alcoholic-beverages, #diabetes, #genetics-and-heredity, #obesity, #pancreatic-cancer, #smoking-and-tobacco, #tests-medical, #weight

Body Odor May Have Smelled Much Worse to Your Ancient Ancestors

Researchers worked out which receptors in your nose detect particular scent molecules, and found evidence of evolutionary change in some of these genes.

#china, #evolution-biology, #genetics-and-heredity, #plos-genetics-journal, #research, #smell-olfaction, #smells-and-odors, #your-feed-science

In New York City Sewage, a Mysterious Coronavirus Signal

For the past year, scientists have been looking for the source of strange coronavirus sequences that have appeared in the city’s wastewater.

#coronavirus-2019-ncov, #genetics-and-heredity, #microbiology, #nature-communications-journal, #new-york-city, #rats, #rodents, #sewers-and-sewage, #your-feed-health, #your-feed-science

After a Mastectomy, Moving Between Gratitude and Grief

Getting diagnosed with a breast cancer gene mutation at 32 was a gift, but left room for disappointment too.

#breast-cancer, #breasts, #cancer, #genetics-and-heredity, #grief-emotion, #mastectomy, #plastic-surgery, #surgery-and-surgeons, #women-and-girls

How Omicron’s Mutations Allow It To Thrive

Thirteen of Omicron’s mutations should have hurt the variant’s chances of survival. Instead, they worked together to make it thrive.

#antibodies, #coronavirus-2019-ncov, #coronavirus-omicron-variant, #evolution-biology, #genetics-and-heredity, #research, #viruses, #your-feed-science

Their DNA Hides a Warning, but They Don’t Want to Know What It Says

Some volunteers for biobanks, which collect genetic information to study health across populations, have been surprised to be informed they carry risky mutations.

#dna-deoxyribonucleic-acid, #ethics-and-official-misconduct, #genetics-and-heredity, #privacy, #research, #tests-medical

In a First, Man Receives a Heart From a Genetically Altered Pig

The breakthrough may lead one day to new supplies of animal organs for transplant into human patients.

#baltimore-md, #cloning, #genetic-engineering, #genetics-and-heredity, #heart, #kidneys, #pigs, #surgery-and-surgeons, #transplants, #university-of-maryland-medical-center, #your-feed-science

How ‘Muscle Memory’ May Help Us Get in Shape

Muscles develop a lasting molecular “memory” of past resistance exercises that helps them bounce back from long periods of inactivity.

#content-type-service, #exercise, #genetics-and-heredity, #muscles, #weight-lifting

The Ghost Wolves of Galveston Island

A population of strange canids in Texas could hold the key to reviving the highly endangered red wolf.

#animal-behavior, #animals, #breeding-of-animals, #coyotes, #endangered-and-extinct-species, #galveston-tex, #galveston-island-tex, #genetics-and-heredity, #research, #vonholdt-bridgett-m-1980, #wolves, #your-feed-animals, #your-feed-photojournalism, #your-feed-science

Sickle Cell Math Is Brutally Simple, but Not Widely Taught

An inexpensive blood test can warn couples if they face one in four odds of having a baby with the disease. No one ever told Lametra Scott and Rickey Buggs about it.

#babies-and-infants, #black-people, #blood, #debaun-michael-r, #discrimination, #genetics-and-heredity, #nashville-tenn, #pregnancy-and-childbirth, #race-and-ethnicity, #sickle-cell-anemia, #tests-medical, #volunteers-and-community-service

How Your DNA Test Could Send a Relative to Jail

Thanks to “genetic genealogy,” solving crimes with genomic databases is becoming mainstream — with some uncomfortable implications for the future of privacy.

#dna-deoxyribonucleic-acid, #false-arrests-convictions-and-imprisonments, #forensic-science, #genealogy, #genetics-and-heredity, #murders-attempted-murders-and-homicides

3,000 Years Ago, Britain Got Half Its Genes From France, DNA Study Suggests

An extensive study of ancient DNA suggests that a wave of newcomers — and perhaps the first Celtic languages — crossed the English Channel three millenniums ago.

#archaeology-and-anthropology, #bronze-age, #dairy-products, #dna-deoxyribonucleic-acid, #england, #france, #genetics-and-heredity, #immigration-and-emigration, #kent-england, #language-and-languages, #nature-journal, #reich-david-e-1974, #your-feed-science

Family in Nigeria Lost 3 Daughters to Sickle Cell. Can They Save a Fourth?

About 150,000 babies are born each year in Nigeria with sickle cell, a deadly disease. Tens of thousands of them die annually before their fifth birthdays.

#africa, #blood, #children-and-childhood, #deaths-fatalities, #debaun-michael-r, #drugs-pharmaceuticals, #genetics-and-heredity, #kano-nigeria, #lancet-the-journal, #national-institutes-of-health, #nigeria, #sickle-cell-anemia, #stroke, #tests-medical

Omicron Is a Dress Rehearsal for the Next Pandemic

America’s response to the variant highlights both how much progress we have made over the past two years — and how much work remains

#bright-rick-a, #centers-for-disease-control-and-prevention, #chiu-charles, #coronavirus-2019-ncov, #coronavirus-delta-variant, #coronavirus-omicron-variant, #coronavirus-risks-and-safety-concerns, #genetics-and-heredity, #laboratories-and-scientific-equipment, #microbiology, #san-francisco-calif, #sewers-and-sewage, #tests-medical, #topol-eric-j, #vaccination-and-immunization, #your-feed-health, #your-feed-science

Why Didn’t the U.S. Detect Omicron Cases Sooner?

Genomic surveillance has improved enormously in recent months, but the system has built-in delays, and blind spots remain.

#centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #coronavirus-omicron-variant, #genetics-and-heredity, #south-africa, #tests-medical, #vaccination-and-immunization, #your-feed-health, #your-feed-science

Why Hasn’t the U.S. Found More Omicron Cases?

Genomic surveillance has improved enormously in recent months, but the system has built-in delays, and blind spots remain.

#centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #coronavirus-omicron-variant, #genetics-and-heredity, #south-africa, #tests-medical, #vaccination-and-immunization, #your-feed-health, #your-feed-science

The Toddler Was Bowlegged, Her Gait Awkward. What Was It?

What the orthopedist saw on the X-rays surprised him.

#bones, #children-and-childhood, #genetics-and-heredity, #tests-medical, #university-of-wisconsin

What I Learned Testing My Dog’s DNA

There are some mysteries that even genetic science can’t explain.

#dna-deoxyribonucleic-acid, #dogs, #genetics-and-heredity, #pets

New ‘Omicron’ Variant Stokes Concern but Vaccines May Still Work

The Omicron variant carries worrisome mutations that may let it evade antibodies, scientists said. But it will take more research to know how it fares against vaccinated people.

#antibodies, #coronavirus-2019-ncov, #genetics-and-heredity, #research, #tests-medical, #vaccination-and-immunization, #world-health-organization, #your-feed-science

Genetic Risks for Cancer Should Not Mean Financial Hardship

People with markers for cancer often need more screenings. But health insurers are not required to fully cover them. 

#breast-cancer, #colon-and-colorectal-cancer, #genetics-and-heredity, #health-insurance-and-managed-care, #tests-medical

The Gene-Synthesis Revolution

Researchers can now design and mass-produce genetic material — a technique that helped build the mRNA vaccines. What could it give us next?

#2021-tech-and-design, #antibiotics, #bacteria, #biology-and-biochemistry, #biotechnology-and-bioengineering, #chemistry, #crispr-dna, #dna-deoxyribonucleic-acid, #genetics-and-heredity, #ginkgo-bioworks-inc, #synthetic-biology

You Should See Her in a Crown. Now You Can See Her Face.

New research is solving mysteries linked to the La Almoloya burial site and revealing a genetic history of an ancient European people.

#archaeology-and-anthropology, #bronze-age, #face, #genetics-and-heredity, #men-and-boys, #research, #software, #spain, #women-and-girls, #your-feed-science

The DNA of Roma People Has Long Been Misused, Scientists Reveal

An op-ed in Nature calls for higher ethical standards in the usage and analysis of genetic information from the Romani, a marginalized group in Europe.

#bulgaria, #dna-deoxyribonucleic-acid, #forensic-science, #genetics-and-heredity, #hungary, #india, #nature-journal, #romani-people, #your-feed-science