John C. Martin, 69, Dies; Led Drugmaker in Breakthroughs

A chemist by training, he turned Gilead Sciences into a leading, and lucrative, innovator with single-pill treatments for H.I.V. and hepatitis C.

#acquired-immune-deficiency-syndrome, #deaths-obituaries, #drugs-pharmaceuticals, #gilead-sciences-inc, #h-i-v, #hepatitis, #martin-john-c-1951-2021, #sovaldi-drug, #tamiflu-drug, #truvada-drug

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Want Vaccines Fast? Suspend Intellectual Property Rights

Otherwise, there won’t be enough shots to go around, even in rich countries.

#astrazeneca-plc, #bayer-ag, #brazil, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #gilead-sciences-inc, #india, #intellectual-property, #inventions-and-patents, #moderna-inc, #pfizer-inc, #remdesivir-drug, #shortages, #south-africa, #united-states, #vaccination-and-immunization, #world-trade-organization

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W.H.O. Rejects Antiviral Drug Remdesivir as a Covid Treatment

In a review of several trials, the World Health Organization found that Gilead’s drug did not improve survival rates for patients nor did it help them recover.

#academic-and-scientific-journals, #bmj-journal, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #gilead-sciences-inc, #remdesivir-drug, #trump-donald-j, #world-health-organization, #your-feed-healthcare

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World Health Organization Rejects Antiviral Drug Remdesivir as Covid-19 Treatment

In a review of several trials, the World Health Organization found that Gilead’s drug did not improve survival rates for patients nor did it help them recover.

#academic-and-scientific-journals, #bmj-journal, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #gilead-sciences-inc, #remdesivir-drug, #trump-donald-j, #world-health-organization, #your-feed-healthcare

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H.I.V. Death Rates Fell by Half 2010-2018, C.D.C. Says

From 2010-2018, significantly fewer people died of H.I.V.-related causes, although survival rates for women and people of color did not improve as much.

#centers-for-disease-control-and-prevention, #gilead-sciences-inc, #homosexuality-and-bisexuality, #morbidity-and-mortality-weekly-report, #research, #southern-states-us, #tests-medical, #women-and-girls, #your-feed-healthcare

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Does Remdesivir Actually Work Against Covid-19?

The evidence shows only that the drug might be effective. That once wasn’t enough for F.D.A. approval.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #remdesivir-drug

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Shot to Prevent H.I.V. Works Better Than Daily Pill in Women

Researchers ended a clinical trial of the drug early because the results were so convincing. The more effective drug would be given in six injections a year instead of as 365 daily pills.

#acquired-immune-deficiency-syndrome, #clinical-trials, #drugs-pharmaceuticals, #gilead-sciences-inc, #truvada-drug, #viiv-healthcare-ltd, #women-and-girls, #your-feed-science

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Gilead’s Covid-19 Drug Is Mediocre. It Will Be a Blockbuster Anyway.

Gilead Sciences said Wednesday that remdesivir, which has been authorized for emergency use since the spring, brought in $873 million in revenues so far this year.

#company-reports, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #remdesivir-drug, #research, #your-feed-science

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F.D.A. Approves Remdesivir as First Drug to Treat Covid-19

The move indicated that the drug had cleared more rigorous hurdles since it was given emergency authorization in May.

#clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #remdesivir-drug

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Remdesivir Fails to Prevent Covid-19 Deaths in Huge Trial

Critics said the study, sponsored by the W.H.O., was too poorly conducted to be definitive.

#coronavirus-2019-ncov, #deaths-fatalities, #drugs-pharmaceuticals, #gilead-sciences-inc, #remdesivir-drug, #united-states, #world-health-organization, #your-feed-science

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Remdesivir Tests for Covid Treatments Enter New Phase

A clinical trial showed that remdesivir helped hospitalized patients. Now researchers are asking whether when the drug is paired with another antiviral drug, patients will recover faster.

#chin-hong-peter, #coronavirus-2019-ncov, #dexamethasone-drug, #gilead-sciences-inc, #immune-system, #interferon-beta-drugs, #national-institute-of-allergy-and-infectious-diseases, #placebos, #remdesivir-drug, #research, #tests-medical, #university-of-california, #your-feed-healthcare

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Remdesivir Could Be in Short Supply. Here’s a Fix.

The federal government must work to ensure adequate supply of the coronavirus drug — and distribute it evenly and transparently.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #generic-brands-and-products, #gilead-sciences-inc, #health-and-human-services-department, #inventions-and-patents, #massachusetts-general-hospital, #remdesivir-drug, #united-states

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A Shot to Protect Against H.I.V.

A drug injected every two months is more effective at preventing H.I.V. infection than a daily pill, scientists report.

#acquired-immune-deficiency-syndrome, #brazil, #clinical-trials, #drugs-pharmaceuticals, #gilead-sciences-inc, #transgender-and-transsexuals, #truvada-drug, #viiv-healthcare-ltd, #women-and-girls, #your-feed-science

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Will We Be Hostages to Drug Makers’ Covid Vaccine Pricing?

The United States is the only developed nation unable to balance cost, efficacy and social good in setting prices.

#biomedical-advanced-research-and-development-authority, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #health-insurance-and-managed-care, #inventions-and-patents, #medicare, #national-institutes-of-health, #prices-fares-fees-and-rates, #vaccination-and-immunization

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Gilead to Test a Version of Remdesivir That Can Be Inhaled

As scientists study the effectiveness of the drug against the coronavirus, others are exploring how to make the potential treatment easier to administer.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #northwell-health, #remdesivir-drug, #steroids, #your-feed-health, #your-feed-science

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Remdesivir Coronavirus Trial: Federal Scientists Finally Publish Data

A clinical trial led to the authorization of the only drug shown to work in Covid-19 patients. But until now, few experts had seen the numbers.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #kalil-andre, #national-institute-of-allergy-and-infectious-diseases, #new-england-journal-of-medicine, #remdesivir-drug, #research, #united-states

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How Upbeat Vaccine News Fueled a Stock Surge, and an Uproar

The desperate hunt for treatments and vaccines has changed how researchers, regulators, drug companies like Moderna, investors and journalists do their jobs.

#academic-and-scientific-journals, #biorxiv, #biotechnology-and-bioengineering, #clinical-trials, #coronavirus-2019-ncov, #gilead-sciences-inc, #medrxiv, #moderna-inc, #news-and-news-media, #remdesivir-drug, #research, #science-and-technology, #stocks-and-bonds, #vaccination-and-immunization, #your-feed-healthcare

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Haphazard Rollout of Coronavirus Drug Frustrates Doctors

Remdesivir was shipped to small hospitals even as besieged medical centers were denied access.

#amerisourcebergen-corp, #birx-deborah-l, #clinical-trials, #coronavirus-2019-ncov, #food-and-drug-administration, #gilead-sciences-inc, #hospitals, #infectious-diseases-society-of-america, #mcenany-kayleigh, #national-institute-of-allergy-and-infectious-diseases, #pence-mike, #remdesivir-drug, #trump-donald-j, #united-states, #united-states-politics-and-government

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How Remdesivir, New Hope for Covid-19 Patients, Was Resurrected

The drug failed as a treatment for hepatitis and Ebola. With federal funding, scientists trained it on the coronavirus.

#colds, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #hepatitis, #influenza, #national-institute-of-allergy-and-infectious-diseases, #remdesivir-drug, #research, #rna-ribonucleic-acid, #sars-severe-acute-respiratory-syndrome, #tests-medical, #trump-donald-j, #united-states, #viruses

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Gilead Claims ‘Positive Data’ to Come From N.I.H. Trial of Remdesivir

Neither the company nor the institutes discussed the data. Another study reported the drug offered no benefit to severely ill patients.

#coronavirus-2019-ncov, #gilead-sciences-inc, #national-institute-of-allergy-and-infectious-diseases, #remdesivir-drug, #your-feed-science

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The Story of Remdesivir

Just as there are no atheists in foxholes, there should be no big-pharma haters in pandemics.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #remdesivir-drug

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With Minimal Evidence, Trump Asks F.D.A. to Study Malaria Drugs for Coronavirus

The president cites “tremendous promise” for existing drugs, but their use against the new virus is unproven.

#american-society-of-health-system-pharmacists, #bayer-ag, #clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #hahn-stephen-m-1960, #trump-donald-j, #united-states-politics-and-government, #your-feed-healthcare

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