The Coronavirus Won’t Stop Evolving When the Vaccine Arrives

The coronavirus is not a shape shifter like the flu virus, but it could become vaccine resistant over time. That prompts researchers to urge vigilance.

#china, #coronavirus-2019-ncov, #denmark, #evolution-biology, #food-and-drug-administration, #immune-system, #moderna-inc, #pfizer-inc, #plos-biology-journal, #university-of-pittsburgh, #vaccination-and-immunization, #your-feed-healthcare

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Their Teeth Fell Out. Was It Another Covid-19 Consequence?

People who already have dental problems may see them aggravated by encounters with the coronavirus, some experts suggest.

#coronavirus-2019-ncov, #gums-mouth, #immune-system, #research, #teeth-and-dentistry, #your-feed-health, #your-feed-healthcare, #your-feed-science

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Quarantine May Negatively Affect Kids’ Immune Systems

Keeping children masked and separated is necessary. It could also undermine their bodies’ ability to learn how to fight pathogens.

#children-and-childhood, #coronavirus-2019-ncov, #immune-system, #vaccination-and-immunization

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Immunity to the Coronavirus May Last Years, New Data Hint

Blood samples from recovered patients suggest a powerful, long-lasting immune response, researchers reported.

#antibodies, #coronavirus-2019-ncov, #immune-system, #la-jolla-calif, #sars-severe-acute-respiratory-syndrome, #vaccination-and-immunization, #your-feed-science

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How Exercise Might Affect Immunity to Lower Cancer Risk

Working out may enhance the immune system’s ability to target and eradicate cancer cells, a study in mice suggests.

#cancer, #elife-journal, #exercise, #immune-system, #karolinska-institute, #research, #running, #tumors

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New Type of Test May Better Discern Immunity to the Coronavirus

The test detects the response of T cells to the virus — an arm of the immune system that may be just as important as antibodies to preventing reinfection.

#antibodies, #coronavirus-2019-ncov, #dna-deoxyribonucleic-acid, #immune-system, #interferon-protein, #microsoft-corp, #research, #tests-medical, #vaccination-and-immunization, #your-feed-science

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The Children Never Had Covid. So Why Did They Have Coronavirus Antibodies?

A provocative study suggests that certain colds may leave antibodies against the new coronavirus, perhaps explaining why children are more protected than adults.

#antibodies, #children-and-childhood, #colds, #coronavirus-2019-ncov, #elledge-stephen-j, #immune-system, #science-journal, #tests-medical

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An Explanation for Some Covid-19 Deaths May Not Be Holding Up

Recent studies have created doubts about an agent in cytokine storms, and suggest that treatments for it may not help.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #immune-system, #jama-internal-medicine-journal, #new-england-journal-of-medicine, #research, #your-feed-health

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Children Produce Weaker Coronavirus Antibodies, Study Finds

The research suggests that children clear the infection much faster than adults and may help explain why many don’t become seriously ill.

#antibodies, #children-and-childhood, #coronavirus-2019-ncov, #coronavirus-risks-and-safety-concerns, #immune-system, #nature-immunology-journal, #research, #your-feed-healthcare

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Why You Shouldn’t Worry About Studies Showing Waning Coronavirus Antibodies

Experts say it’s normal for levels of antibodies to drop after clearing an infection, and that they represent just one arm of the immune response against a virus.

#antibodies, #coronavirus-2019-ncov, #immune-system, #tests-medical, #vaccination-and-immunization, #your-feed-science

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Some Covid Survivors Have Antibodies That Attack the Body, not Virus

New research found ‘autoantibodies’ similar to those in lupus and rheumatoid arthritis patients. But patients may also benefit from treatments for those autoimmune diseases.

#antibodies, #autoimmune-diseases, #chronic-condition-health, #coronavirus-2019-ncov, #dna-deoxyribonucleic-acid, #immune-system, #lupus-erythematosus, #research, #rheumatoid-arthritis, #rna-ribonucleic-acid, #your-feed-health, #your-feed-science

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A Malaria Mystery, Partly Solved: What Happens When the Rains End?

A study in Mali suggests that malaria parasites hide out during the dry season by altering the properties of red blood cells.

#africa, #immune-system, #malaria, #mosquitoes, #nature-medicine-journal, #parasites, #spleen, #your-feed-health, #your-feed-science

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Coronavirus Reinfections Are Real but Very, Very Rare

A case in Nevada has spurred new concerns that people who have recovered from the infection may still be vulnerable. That’s unlikely, experts say.

#coronavirus-2019-ncov, #disease-rates, #europe, #immune-system, #lancet-infectious-diseases-the-journal, #nevada, #united-states, #vaccination-and-immunization, #your-feed-science

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The Race for a Super-Antibody Against the Coronavirus

A network of scientists is chasing the pandemic’s holy grail: an antibody that protects against not just the virus, but also related pathogens that may threaten humans.

#antibodies, #astrazeneca-plc, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #einstein-albert-college-of-medicine, #elderly, #eli-lilly-and-company, #factories-and-manufacturing, #food-and-drug-administration, #immune-system, #nursing-homes, #regeneron-pharmaceuticals-inc, #roche-holding-ag, #sars-severe-acute-respiratory-syndrome, #trump-donald-j, #united-states, #united-states-army-medical-research-institute-of-infectious-diseases, #vaccination-and-immunization, #walker-laura, #your-feed-science

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Pandemic Is Far From Over, Experts Say, Despite Trump Allies’ Claims

The C.D.C. and leading experts have concluded, using different scientific methods, that as many as 90 percent of Americans are still vulnerable to infection.

#antibodies, #atlas-scott-w, #cell-journal, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #disease-rates, #fauci-anthony-s, #fox-broadcasting-co, #frieden-thomas-r, #immune-system, #ingraham-laura-a, #limbaugh-rush, #lipsitch-marc, #masks, #medicine-and-health, #osterholm-michael-t, #paul-rand, #trump-donald-j, #your-feed-health, #your-feed-science

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How Do Children Fight Off the Coronavirus?

The secret may lie in an “innate” immune response that targets unrecognized invaders, scientists say.

#children-and-childhood, #coronavirus-2019-ncov, #disease-rates, #immune-system, #montefiore-medical-center, #new-york-city, #pediatric-inflammatory-multisystem-syndrome-pims, #research, #respiratory-distress-syndrome, #science-translational-medicine-journal, #your-feed-science

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He Had Recurring Pain for Nearly a Decade

The muscles from his buttock down to his calf felt as if they were on fire. He saw countless specialists, but nothing really seemed to help. What could it possibly be?

#arthritis, #colitis, #crohns-disease, #digestive-tract, #immune-system

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Covering Ebola Didn’t Prepare Me for This: I Volunteered for the Covid-19 Vaccine Trial

George Washington University Hospital invited me to participate in Moderna’s vaccine trial because I am triple-risk: a Black woman, a Type 1 diabetic and asthmatic.

#clinical-trials, #content-type-service, #coronavirus-2019-ncov, #fauci-anthony-s, #george-washington-university, #immune-system, #moderna-inc, #placebos, #rna-ribonucleic-acid, #vaccination-and-immunization

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The Coronavirus Is Mutating, and That’s Fine (So Far)

SARS-CoV-2 has been slowly changing in small ways, without getting more dangerous.

#australia, #cell-journal, #china, #content-type-service, #coronavirus-2019-ncov, #evolution-biology, #hong-kong, #immune-system, #influenza, #italy, #mutation, #new-south-wales-australia, #rna-ribonucleic-acid, #rumors-and-misinformation, #sars-severe-acute-respiratory-syndrome, #vaccination-and-immunization, #victoria-australia, #viruses, #wuhan-china

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What if We Have to Wait Years for a Coronavirus Vaccine?

A silver-bullet vaccine is far from guaranteed. But it’s also not the only way out of the pandemic.

#coronavirus-2019-ncov, #coronavirus-reopenings, #debatable, #epidemics, #fauci-anthony-s, #immune-system, #tuberculosis, #viruses

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Is Staying Home Harming Your Child’s Immune System?

Why exposure to other germy kids might matter.

#child-care, #children-and-childhood, #coronavirus-risks-and-safety-concerns, #cytomegalovirus, #immune-system, #parenting, #respiratory-diseases, #respiratory-syncytial-virus-rsv

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How the Coronavirus Attacks the Brain

It’s not just the lungs — the pathogen may enter brain cells, causing symptoms like delirium and confusion, scientists reported.

#brain, #coronavirus-2019-ncov, #delirium, #immune-system, #muotri-alysson, #nerves-and-nervous-system, #stevens-robert, #stroke, #your-feed-science, #zika-virus

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A New Theory Asks: Could a Mask Be a Crude ‘Vaccine’?

Scientists float a provocative — and unproven — idea: that masks expose the wearer to just enough of the virus to spark a protective immune response.

#coronavirus-2019-ncov, #coronavirus-risks-and-safety-concerns, #immune-system, #masks, #protective-clothing-and-gear, #vaccination-and-immunization, #your-feed-health, #your-feed-science

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How the Aging Immune System Makes Older People Vulnerable to Covid-19

As we age, the immune system begins to shift into a heightened state of alert, dialing up inflammation and running out of certain immune cells.

#coronavirus-2019-ncov, #dexamethasone-drug, #elderly, #immune-system, #research, #vaccination-and-immunization, #your-feed-science

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Scientists Report Steroids Can Be Lifesaving for Covid-19 Patients

New data in hand, the W.H.O. recommended that doctors give the drugs to critically ill patients worldwide.

#coronavirus-2019-ncov, #dexamethasone-drug, #immune-system, #jama-journal-of-american-medical-assn, #remdesivir-drug, #steroids, #vanderbilt-university, #world-health-organization, #your-feed-science

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Why Does the Coronavirus Hit Men Harder? A New Clue

Women produce a more powerful immune response than do men, a new study finds.

#age-chronological, #coronavirus-2019-ncov, #hamburg-germany, #immune-system, #nature-journal, #proteins, #vaccination-and-immunization, #women-and-girls, #yale-university, #your-feed-science

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A Woman May Have Been Cured of H.I.V. Without Medical Treatment

In dozens of other patients who suppress the virus without drugs, it seems to have been cornered in parts of the genome where it cannot reproduce, scientists reported.

#acquired-immune-deficiency-syndrome, #bone-marrow, #genetics-and-heredity, #harvard-university, #immune-system, #nature-journal, #transplants, #your-feed-science

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Exercise May Boost Your Vaccine Response

Two new studies of elite athletes found that working out amplifies the immune response to a flu shot.

#athletics-and-sports, #badminton, #colds, #coronavirus-2019-ncov, #cycling-road, #exercise, #immune-system, #influenza, #swimming, #track-and-field, #vaccination-and-immunization, #wrestling

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How Bacteria-Eating Bacteria Could Help Win the War Against Germs

While microscopic and little known, predatory bacteria are among the world’s fiercest and most effective hunters.

#antibiotics, #bacteria, #drug-resistance-microbial, #immune-system, #microbiology, #your-feed-health, #your-feed-science

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Why Getting Children Flu Shots Is Even More Important This Year

Doctors offer advice on when and where to safely get vaccinated.

#american-academy-of-pediatrics, #centers-for-disease-control-and-prevention, #children-and-childhood, #coronavirus-2019-ncov, #immune-system, #influenza, #parenting, #vaccination-and-immunization

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Remdesivir Tests for Covid Treatments Enter New Phase

A clinical trial showed that remdesivir helped hospitalized patients. Now researchers are asking whether when the drug is paired with another antiviral drug, patients will recover faster.

#chin-hong-peter, #coronavirus-2019-ncov, #dexamethasone-drug, #gilead-sciences-inc, #immune-system, #interferon-beta-drugs, #national-institute-of-allergy-and-infectious-diseases, #placebos, #remdesivir-drug, #research, #tests-medical, #university-of-california, #your-feed-healthcare

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Scientists See Signs of Lasting Immunity to Covid-19, Even After Mild Infections

New research indicates that human immune system cells are storing information about the coronavirus so they can fight it off again.

#antibodies, #cell-journal, #coronavirus-2019-ncov, #immune-system, #nature-journal, #your-feed-health, #your-feed-science

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How Covid Sends Some Bodies to War With Themselves

Many Covid-19 patients may be dying from their immune response to the virus, not from the virus itself. Can science figure out how to save them?

#coronavirus-2019-ncov, #immune-system, #remdesivir-drug, #research

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The Coronavirus Is New, but Your Immune System Might Still Recognize It

Some people carry immune cells called T cells that can capitalize on the virus’s resemblance to other members of its family tree.

#coronavirus-2019-ncov, #immune-system, #research, #vaccination-and-immunization, #your-feed-health, #your-feed-science

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Novavax’s New Covid-19 Vaccine Studies Praised By Scientists

The company has received a $1.6 billion grant from the government’s Operation Warp Speed to have 100 million doses ready by early 2021.

#clinical-trials, #coronavirus-2019-ncov, #immune-system, #novavax-inc, #public-private-sector-cooperation, #research, #vaccination-and-immunization

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So You Want to Volunteer in a Coronavirus Vaccine Trial

How do you sign up? Will you get paid? Who will cover the costs if you get sick? Here’s a look at the basics.

#coronavirus-2019-ncov, #immune-system, #placebos, #research, #vaccination-and-immunization

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Scientists Uncover Biological Signatures of the Worst Covid-19 Cases

Studies of patients with severe cases of Covid-19 show the immune system lacks its usual coordinated response.

#coronavirus-2019-ncov, #dexamethasone-drug, #immune-system, #microbiology, #nature-medicine-journal, #research, #science-journal, #viruses, #your-feed-health, #your-feed-science

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A Coronavirus Vaccine Is Coming. Just Don’t Call It ‘Warp Speed.’

Scientists need to show us the data. And that’s exactly what they’re working on.

#coronavirus-2019-ncov, #immune-system, #research, #vaccination-and-immunization

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Scared That Covid-19 Immunity Won’t Last? Don’t Be

Dropping antibody counts aren’t a sign that our immune system is failing against the coronavirus, nor an omen that we can’t develop a viable vaccine.

#antibodies, #coronavirus-2019-ncov, #disease-rates, #human-papillomavirus-hpv, #immune-system, #measles, #preventive-medicine, #sexually-transmitted-diseases, #vaccination-and-immunization, #viruses

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The Male Anglerfish’s Evolutionary Solution to Female Rejection

Commingling tissues and blood would normally prompt a massive immune response. These deep sea lovers found a workaround.

#biology-and-biochemistry, #evolution-biology, #fish-and-other-marine-life, #genetics-and-heredity, #immune-system, #reproduction-biological, #research, #science-journal, #your-feed-animals, #your-feed-science

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Old Vaccines May Stop the Coronavirus, Study Hints. Scientists Are Skeptical.

Certain vaccines may provide broad protection against infections. But new research doesn’t prove these vaccines can turn back the coronavirus, experts said.

#coronavirus-2019-ncov, #immune-system, #mayo-clinic, #vaccination-and-immunization, #your-feed-science

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The Coronavirus Could Dodge Some Treatments, Study Suggests

A laboratory experiment hints at some of the ways the virus might elude antibody treatments. Combining therapies could help, experts said.

#antibodies, #coronavirus-2019-ncov, #drug-resistance-microbial, #immune-system, #medrxiv, #research, #vaccination-and-immunization, #viruses, #your-feed-science

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Your Coronavirus Antibodies Are Disappearing. Should You Care?

Declining antibody levels do not mean less immunity, experts say. Besides, two widely used tests may detect the wrong antibodies.

#abbott-laboratories, #antibodies, #coronavirus-2019-ncov, #immune-system, #laboratory-corporation-of-america-holdings, #proteins, #quest-diagnostics, #roche-holding-ag, #tests-medical, #your-feed-science

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Viking Age Smallpox Complicates Story of Viral Evolution

An extinct version of the smallpox virus dating to 1,400 years ago prompts speculation about viruses becoming more lethal over time.

#cambridge-university, #coronavirus-2019-ncov, #dna-deoxyribonucleic-acid, #evolution-biology, #genetics-and-heredity, #immune-system, #science-journal, #smallpox, #viruses, #your-feed-science

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Meet the 4 frontrunners in the COVID-19 vaccine race

A volunteer receives an injection from a medical worker during the country's first human clinical trial for a potential vaccine against COVID-19 at the Baragwanath Hospital on June 28, 2020 in Soweto, South Africa. It is reported that Africa's first COVID-19 vaccine trial began on June 24 in South Africa. The vaccine, developed by Oxford University's (UK) Jenner Institute, will inoculate 2,000 South Africans.

Enlarge / A volunteer receives an injection from a medical worker during the country’s first human clinical trial for a potential vaccine against COVID-19 at the Baragwanath Hospital on June 28, 2020 in Soweto, South Africa. It is reported that Africa’s first COVID-19 vaccine trial began on June 24 in South Africa. The vaccine, developed by Oxford University’s (UK) Jenner Institute, will inoculate 2,000 South Africans. (credit: Getty | Felix Dlangamandla)

Researchers have now reported data from early (and small) clinical trials of four candidate COVID-19 vaccines.

So far, the data is positive. The vaccines appear to be generally safe, and they spur immune responses against the novel coronavirus, SARS-CoV-2. But whether these immune responses are enough to protect people from infection and disease remains an important unknown.

The four candidates are now headed to larger trials—phase III trials—that will put them to the ultimate test: can they protect people from COVID-19 and end this pandemic?

Read 35 remaining paragraphs | Comments

#antibodieis, #astrazeneca, #cansino, #china, #covid-19, #features, #immune-system, #immune-system-response, #immunity, #immunology, #moderna, #mrna, #pfizer, #public-health, #sars-cov-2, #science, #vaccines

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Can You Become Reinfected With Covid? It’s Very Unlikely, Experts Say

Reports of reinfection instead may be cases of drawn-out illness. A decline in antibodies is normal after a few weeks, and people are protected from the coronavirus in other ways.

#antibodies, #coronavirus-2019-ncov, #disease-rates, #hotez-peter-j, #immune-system, #lipsitch-marc, #rumors-and-misinformation, #sars-severe-acute-respiratory-syndrome, #tests-medical, #vaccination-and-immunization, #your-feed-healthcare

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First Coronavirus Vaccine Tested in Humans Shows Early Promise

The vaccine, developed by government scientists and Moderna, a biotech company, appeared safe and provoked an immune response in 45 people in a study.

#coronavirus-2019-ncov, #immune-system, #moderna-inc, #national-institute-of-allergy-and-infectious-diseases, #new-england-journal-of-medicine, #vaccination-and-immunization, #your-feed-science

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Nasal Coronavirus Vaccines May Work Better Than Injected Ones, Researchers Say

Some experts say a vaccine puffed in the nose would be better at protecting people from infection. But nasal vaccines won’t be ready right away.

#coronavirus-2019-ncov, #immune-system, #vaccination-and-immunization, #your-feed-science

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How the Coronavirus Short-Circuits the Immune System

In a disturbing parallel to H.I.V., the coronavirus can cause a depletion of important immune cells, recent studies found.

#acquired-immune-deficiency-syndrome, #coronavirus-2019-ncov, #immune-system, #kings-college, #nature-medicine-journal

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Breakthrough Drug for Covid-19 May Be Risky for Mild Cases

That study about dexamethasone has arrived with a big asterisk: While it appears to help severely ill patients, it harms others.

#clinical-trials, #coronavirus-2019-ncov, #dexamethasone-drug, #drugs-pharmaceuticals, #immune-system, #oxford-university, #steroids, #your-feed-science

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