Behind the Scenes, McKinsey Guided Companies at the Center of the Opioid Crisis

The consulting firm offered clients “in-depth experience in narcotics,” from poppy fields to pills more powerful than Purdue’s OxyContin.

#acquired-immune-deficiency-syndrome, #appalachian-region, #centers-for-disease-control-and-prevention, #consultants, #drug-abuse-and-traffic, #drug-enforcement-administration, #drugs-pharmaceuticals, #endo, #food-and-drug-administration, #johnsonjohnson, #mckinseyco, #opana, #opioids-and-opiates, #oxycontin-drug, #pain-relieving-drugs, #poppies, #purdue-pharma, #united-states

FDA Further Limits Johnson & Johnson Covid Vaccine

The agency said the move reflected an updated analysis of the risk of a rare but serious blood-clotting condition in people who get the vaccine.

#coronavirus-2019-ncov, #food-and-drug-administration, #johnsonjohnson, #vaccination-and-immunization

F.D.A. Allows Second Coronavirus Boosters for Everyone 50 and Older

People in the age group can get the additional shot at least four months after their first booster. Those 12 and older with certain immune deficiencies are also eligible.

#biontech-se, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #pfizer-inc, #united-states-politics-and-government, #vaccination-and-immunization

The J.&J. Vaccine Holds Its Own as Virus Data Grows

Once dismissed as less effective, the vaccine now seems to be preventing infections and illness about as well as the two mRNA options.

#biontech-se, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #disease-rates, #johnsonjohnson, #moderna-inc, #pfizer-inc, #vaccination-and-immunization, #your-feed-science

Companies Finalize $26 Billion Deal With States and Cities to End Opioid Lawsuits

The first checks could be cut in April. The money — from the nation’s three major pharmaceutical distributors and Johnson & Johnson — will be used for addiction treatment and prevention.

#amerisourcebergen-corp, #cardinal-health-inc, #compensation-for-damages-law, #drug-abuse-and-traffic, #drugs-pharmaceuticals, #janssen-pharmaceutica, #johnsonjohnson, #local-government, #mckesson-corporation, #opioids-and-opiates, #states-us, #suits-and-litigation-civil, #your-feed-science

Trump’s Strategy: ‘Confuse and Obscure’

Readers say lying and concealment are Mr. Trump’s response to investigations of Jan. 6 and his finances. Also: Russia, Ukraine and Hungary; Covid vaccines.

#biden-joseph-r-jr, #coronavirus-2019-ncov, #hungary, #johnsonjohnson, #mazars-usa, #rumors-and-misinformation, #russia, #trump-donald-j, #ukraine, #united-states-politics-and-government, #vaccination-and-immunization

J.&J. Pauses Production of Its Covid Vaccine Despite Persistent Need

A crucial Johnson & Johnson plant has stopped making its Covid vaccine, though the company says it has millions of doses in inventory.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #factories-and-manufacturing, #johnsonjohnson, #vaccination-and-immunization

Tribes Reach $590 Million Opioid Settlement With Johnson & Johnson

Money from the tentative deal would go toward addiction and treatment and would be overseen by Native American tribal leaders.

#drugs-pharmaceuticals, #johnsonjohnson, #native-americans, #opioids-and-opiates, #purdue-pharma, #suits-and-litigation-civil

Teva Pharmaceuticals Found Liable in Landmark Opioid Trial

The case was the first of its kind, targeting every point of the prescription opioid supply chain, from manufacturers to pharmacy chains that filled prescriptions.

#allergan-inc, #centers-for-disease-control-and-prevention, #central-islip-ny, #compensation-for-damages-law, #drug-abuse-and-traffic, #drugs-pharmaceuticals, #johnsonjohnson, #long-island-ny, #nassau-county-ny, #new-york-state, #opioids-and-opiates, #suffolk-county-ny, #suits-and-litigation-civil, #teva-pharmaceutical-industries-ltd

J. & J. Booster Protects Against Severe Omicron, Study Says

Two shots of the vaccine reduced the risk of hospitalization from the fast-spreading variant by 85 percent, a clinical trial found.

#clinical-trials, #coronavirus-2019-ncov, #coronavirus-omicron-variant, #drugs-pharmaceuticals, #johnsonjohnson, #research, #south-africa, #vaccination-and-immunization

Beneath a Covid Vaccine Debacle, 30 Years of Government Culpability

Washington has rejected plans to revamp vaccine preparedness for decades and repeatedly paid a price. The Biden administration is at a similar crossroads.

#anthrax, #astrazeneca-plc, #biden-joseph-r-jr, #biological-and-chemical-warfare, #biomedical-advanced-research-and-development-authority, #botulism, #coronavirus-2019-ncov, #defense-department, #drugs-pharmaceuticals, #el-hibri-fuad, #emergent-biosolutions-inc, #epidemics, #food-and-drug-administration, #gaithersburg-md, #government-contracts-and-procurement, #johnsonjohnson, #moderna-inc, #politics-and-government, #public-private-sector-cooperation, #smallpox, #stockpiling, #united-states, #vaccination-and-immunization

C.D.C. Panel Recommends Other Covid Vaccines Over J.&J.’s Shots

A committee of experts voted on a preference for the Moderna or Pfizer immunizations, citing the risk of blood clots linked to Johnson & Johnson’s product.

#advisory-committee-on-immunization-practices, #astrazeneca-plc, #blood-clots, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #deaths-fatalities, #food-and-drug-administration, #johnsonjohnson, #vaccination-and-immunization

A C.D.C. panel weighs the risks of blood clots linked to the J.&J. vaccine.

Public health experts cite concerns about the increased incidence of a rare but potentially serious blood clotting condition among those who received the company’s shot.

#advisory-committee-on-immunization-practices, #blood-clots, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #food-and-drug-administration, #johnsonjohnson, #vaccination-and-immunization

C.D.C. Panel Will Discuss Blood Clot Risk Linked to J.&J.’s Vaccine

On Thursday, agency advisers will review updated figures showing roughly nine deaths from the rare disorder, according to a federal official.

#blood-clots, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #johnsonjohnson, #vaccination-and-immunization

South African Company Nears License to Sell J. & J. Covid Shot Across Africa

The new agreement makes Aspen Pharmacare the first African company to market a Covid vaccine on the continent. But it stops short of allowing Aspen to make the ingredients in the vaccine.

#africa, #aspen-pharmacare, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #intellectual-property, #international-trade-and-world-market, #johnsonjohnson, #south-africa, #vaccination-and-immunization, #your-feed-science

Johnson & Johnson Will Break Itself Up Into Two Companies

The corporate giant said it would spin off its consumer products division, leaving the company to manufacture and market drugs and medical devices.

#corporations, #johnsonjohnson, #medical-devices

Oklahoma Supreme Court Throws Out $465 Million Opioid Ruling Against J.&J.

The 5-1 decision is a setback for those who are fighting to hold big drug makers accountable for the opioid epidemic.

#drugs-pharmaceuticals, #johnsonjohnson, #oklahoma, #opioids-and-opiates, #suits-and-litigation-civil, #your-feed-healthcare

Federal Government Cuts Ties With Troubled Vaccine Maker

Emergent BioSolutions ruined millions of doses of Covid-19 vaccines. Now its $600 million deal is canceled.

#anthrax, #astrazeneca-plc, #coronavirus-2019-ncov, #emergent-biosolutions-inc, #food-and-drug-administration, #government-contracts-and-procurement, #health-and-human-services-department, #johnsonjohnson, #kramer-robert-g, #vaccination-and-immunization

Opioid Makers Win Major Victory in California Trial

In one of the first cases to be brought against drug manufacturers over the crisis, a judge ruled that there was “simply no evidence” the companies were liable in the epidemic.

#allergan-inc, #drugs-pharmaceuticals, #endo-pharmaceuticals-holdings-inc, #johnsonjohnson, #opioids-and-opiates, #teva-pharmaceutical-industries-ltd, #your-feed-science

Are Vaccine Boosters Widely Needed? Some Federal Advisers Have Misgivings.

“In our hearts, I think people don’t quite agree with this notion of a booster dose,” said one leading vaccine expert.

#advisory-committee-on-immunization-practices, #biontech-se, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #pfizer-inc, #vaccination-and-immunization, #your-feed-science

C.D.C. Recommends Covid Booster Shots for Millions of Americans

Recipients of the Moderna and the J.&J. vaccines may receive extra doses, although the shots continue to prevent illness and death.

#advisory-committee-on-immunization-practices, #biontech-se, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #disease-rates, #immune-system, #johnsonjohnson, #moderna-inc, #pfizer-inc, #united-states-politics-and-government, #vaccination-and-immunization, #your-feed-science

F.D.A. Authorizes Moderna and Johnson & Johnson Booster Shots

The agency will also allow vaccine recipients to pick which vaccine they want as a booster, endorsing a mix-and-match approach.

#biontech-se, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #pfizer-inc, #united-states-politics-and-government, #vaccination-and-immunization

Mix-and-Match Covid Boosters: Why They Just Might Work

The F.D.A. may authorize booster shots of vaccines different from the ones that Americans originally received. The science behind the move is promising.

#antibodies, #clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #immune-system, #johnsonjohnson, #moderna-inc, #pfizer-inc, #vaccination-and-immunization

F.D.A. to Allow ‘Mix and Match’ Approach for Covid Booster Shots

The agency may act this week, when it is expected to authorize booster shots for recipients of the Moderna and Johnson & Johnson vaccines.

#centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #national-institutes-of-health, #pfizer-inc, #regulation-and-deregulation-of-industry, #united-states-politics-and-government, #vaccination-and-immunization

F.D.A. Panel Unanimously Recommends Johnson & Johnson Booster Shots

But many panel members said J. & J. recipients might also benefit from the option of a Pfizer-BioNTech or Moderna booster, an action that an F.D.A. official said was possible.

#centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #pfizer-inc, #regulation-and-deregulation-of-industry, #vaccination-and-immunization

Where Things Stand on Boosters for Three Vaccines in the U.S.

Confused about who can get a booster shot of which vaccine, and what the F.D.A.’s advisers on vaccines are voting on this week? This scorecard may help.

#biontech-se, #coronavirus-2019-ncov, #disease-rates, #drugs-pharmaceuticals, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #pfizer-inc, #regulation-and-deregulation-of-industry, #vaccination-and-immunization

Johnson & Johnson Subsidiary Seeks Bankruptcy Protection to Handle Talc Product Claims

The company said the Chapter 11 bankruptcy filing was intended to resolve current and future claims that its products cause cancer.

#bankruptcies, #boy-scouts, #johnsonjohnson, #ovarian-cancer, #suits-and-litigation-civil, #usa-gymnastics

Data from Federal Scientists Raise Questions About J.&J. Booster Shots

People who have received the company’s one-shot vaccine may benefit from a booster with another brand. F.D.A. advisers will discuss the data on Friday.

#clinical-trials, #coronavirus-2019-ncov, #coronavirus-delta-variant, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #national-institutes-of-health, #pfizer-inc, #research, #united-states-politics-and-government, #vaccination-and-immunization, #your-feed-healthcare

Moderna, Racing for Profits, Keeps Covid Vaccine Out of Reach of Poor

Some poorer countries are paying more and waiting longer for the company’s vaccine than the wealthy — if they have access at all.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #government-contracts-and-procurement, #income-inequality, #johnsonjohnson, #moderna-inc, #pfizer-inc, #third-world-and-developing-countries, #vaccination-and-immunization

Moderna vs. Pfizer: Both Knockouts, but One Seems to Have the Edge

A series of studies found that the Moderna vaccine seemed to be more protective over the long term than the Pfizer-BioNTech vaccine. Here’s why.

#biontech-se, #clinical-trials, #coronavirus-2019-ncov, #immune-system, #johnsonjohnson, #journal-of-the-american-medical-assn, #moderna-inc, #pfizer-inc, #united-states, #vaccination-and-immunization, #your-feed-science

Health Officials Advise White House to Scale Back Booster Plan for Now

Federal regulators warned on Thursday they may not have enough data to recommend boosters for anyone except certain recipients of the Pfizer vaccine by late September.

#centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #national-institutes-of-health, #pfizer-inc, #united-states-politics-and-government, #vaccination-and-immunization

An Experimental H.I.V. Vaccine Fails in Africa

Researchers ended a large trial in South Africa after finding that an experimental vaccine offered little protection.

#acquired-immune-deficiency-syndrome, #africa, #clinical-trials, #drugs-pharmaceuticals, #johnsonjohnson, #south-africa, #vaccination-and-immunization, #your-feed-science

Biden Falls Short on Pledge for U.S. to Be the World’s Vaccine ‘Arsenal,’ Experts Say

Congress appropriated $16 billion to ramp up Covid-19 countermeasures, but a new report found that the Biden administration had spent very little of it on expanding vaccine manufacturing capacity.

#american-rescue-plan-2021, #biden-joseph-r-jr, #biontech-se, #coronavirus-2019-ncov, #covax, #drugs-pharmaceuticals, #johnsonjohnson, #moderna-inc, #novavax-inc, #pfizer-inc, #united-states-politics-and-government, #vaccination-and-immunization

What to Know About Boosters if You Got the Johnson & Johnson Vaccine

Health experts say that boosters are likely to be needed eventually and that more data should be available in the next several weeks.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #johnsonjohnson, #moderna-inc, #murthy-vivek-h, #pfizer-inc, #south-africa, #united-states, #vaccination-and-immunization, #your-feed-health

F.D.A. Aims to Give Final Approval to Pfizer Vaccine by Early Next Month

The Food and Drug Administration’s move is expected to kick off more vaccination mandates for hospital workers, college students and federal troops.

#biontech-se, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #pfizer-inc, #united-states-politics-and-government, #vaccination-and-immunization

Biden Officials Now Expect Vulnerable Americans to Need Booster Shots

The growing consensus that at least some Americans will need a booster is partly tied to research suggesting that Pfizer’s vaccine is less effective after about six months.

#centers-for-disease-control-and-prevention, #clinical-trials, #coronavirus-2019-ncov, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #offit-paul-a, #pfizer-inc, #vaccination-and-immunization

J.&J. Vaccine May Be Less Effective Against Delta, Study Suggests

Many who received the shot may need to consider boosters, the authors said. But federal health officials do not recommend second doses.

#astrazeneca-plc, #blood-clots, #coronavirus-2019-ncov, #disease-rates, #drugs-pharmaceuticals, #food-and-drug-administration, #immune-system, #johnsonjohnson, #moderna-inc, #pfizer-inc, #research, #vaccination-and-immunization, #your-feed-science

F.D.A. Attaches Warning of Rare Nerve Syndrome to Johnson & Johnson Covid Vaccine

Federal regulators concluded that the risk of developing the syndrome was low, and that the benefits of the vaccine still strongly outweigh it.

#centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #disease-rates, #drugs-pharmaceuticals, #food-and-drug-administration, #guillain-barre-syndrome, #johnsonjohnson, #regulation-and-deregulation-of-industry, #united-states-politics-and-government, #vaccination-and-immunization, #your-feed-healthcare, #your-feed-science

Emergent BioSolutions Faces Investor Revolt Over Botched Vaccines

In the latest shareholder lawsuit, a pension fund accused executives at Emergent BioSolutions of insider trading. The company, under investigation by Congress, has halted manufacturing of Covid-19 vaccines at its Baltimore factory at regulators’ request.

#baltimore-md, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #el-hibri-fuad, #emergent-biosolutions-inc, #factories-and-manufacturing, #johnsonjohnson, #maryland, #securities-and-commodities-violations, #shareholder-rights-and-activism, #stocks-and-bonds, #suits-and-litigation-civil, #vaccination-and-immunization

Biotech Company That Botched Vaccines Faces Investor Revolt

In the latest shareholder lawsuit, a pension fund accused executives at Emergent BioSolutions of insider trading. The company, under investigation by Congress, has halted manufacturing of Covid-19 vaccines at its Baltimore factory at regulators’ request.

#baltimore-md, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #el-hibri-fuad, #emergent-biosolutions-inc, #factories-and-manufacturing, #johnsonjohnson, #maryland, #securities-and-commodities-violations, #shareholder-rights-and-activism, #stocks-and-bonds, #suits-and-litigation-civil, #vaccination-and-immunization

Overnight Vaccination Drive in Rome Reaches Out to the ‘Most Fragile’

Nearly 900 people showed up for music, free espresso and cornetti, and a chance for protection against the coronavirus.

#coronavirus-2019-ncov, #homeless-persons, #italy, #johnsonjohnson, #romani-people, #rome-italy, #vaccination-and-immunization

Finally, Experts Break the Silence on J.&J. Boosters

For too long, those who got the one-dose vaccine were left in the dark.

#coronavirus-2019-ncov, #coronavirus-risks-and-safety-concerns, #johnsonjohnson, #medicine-and-health, #pfizer-inc, #vaccination-and-immunization

Johnson & Johnson Vaccine Protects Against Delta Variant, Company Reports

The vaccine also produced long-lasting immune responses, researchers said. Booster shots seem unnecessary, at least for now.

#clinical-trials, #coronavirus-2019-ncov, #immune-system, #johnsonjohnson, #moderna-inc, #pfizer-inc, #united-states, #vaccination-and-immunization, #your-feed-science

An Opioid Case Like No Other: New York vs the Entire Supply Chain

New York’s sweeping lawsuit is the first opioid case in which a jury rather than a judge will decide the outcome.

#amerisourcebergen-corp, #drug-abuse-and-traffic, #drugs-pharmaceuticals, #johnsonjohnson, #long-island-ny, #mckesson-corporation, #new-york-state, #opioids-and-opiates, #oxycontin-drug, #purdue-pharma, #sackler-family, #suits-and-litigation-civil, #teva-pharmaceutical-industries-ltd, #walgreen-co

Three Studies, One Result: Vaccines Point the Way Out of the Pandemic

New scientific research underscores the effectiveness of vaccines and their versatility in the fight against the coronavirus.

#antibodies, #astrazeneca-plc, #biontech-se, #clinical-trials, #coronavirus-2019-ncov, #disease-rates, #immune-system, #johnsonjohnson, #moderna-inc, #nature-journal, #pfizer-inc, #research, #united-states, #vaccination-and-immunization, #your-feed-science

Johnson & Johnson to Pay New York $230 Million to Settle Opioid Case

The settlement agreement came just days before opening arguments in a sweeping trial of several defendants, including the company.

#compensation-for-damages-law, #drugs-pharmaceuticals, #duragesic-drug, #james-letitia, #janssen-pharmaceutica, #johnsonjohnson, #new-york-state, #opioids-and-opiates, #oxycontin-drug, #suits-and-litigation-civil

High Hopes for Johnson & Johnson’s Covid Vaccine Have Fizzled in the U.S.

Production problems and a brief pause on its use kept the one-dose vaccine from becoming the game changer that health officials across the country believed it would be.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #emergent-biosolutions-inc, #factories-and-manufacturing, #gorsky-alex, #johnsonjohnson, #regulation-and-deregulation-of-industry, #rural-areas, #shutdowns-institutional, #states-us, #vaccination-and-immunization

Vaccine Maker Earned Record Profits but Delivered Disappointment in Return

Emergent BioSolutions was awarded a $628 million federal contract with no competitive bidding. Top executives received big bonuses while factories mostly sat idle and tens of millions of Covid-19 doses were thrown away.

#astrazeneca-plc, #baltimore-md, #coronavirus-2019-ncov, #emergent-biosolutions-inc, #food-and-drug-administration, #gaithersburg-md, #government-contracts-and-procurement, #health-and-human-services-department, #johnsonjohnson, #kadlec-robert-p, #maryland, #michigan, #rockville-md, #trump-donald-j, #vaccination-and-immunization

FDA Details Failures at Baltimore Plant That Spoiled Vaccine Doses

The F.D.A. advised Johnson & Johnson on Friday that it should throw out the equivalent of 60 million doses produced at the Baltimore plant.

#astrazeneca-plc, #baltimore-md, #coronavirus-2019-ncov, #emergent-biosolutions-inc, #factories-and-manufacturing, #food-and-drug-administration, #internal-essential, #johnsonjohnson, #vaccination-and-immunization

F.D.A. Tells Johnson & Johnson That60 Million Vaccine Doses Cannot Be Used

The agency has not decided whether to allow a troubled vaccine factory in Baltimore to reopen.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #emergent-biosolutions-inc, #food-and-drug-administration, #johnsonjohnson, #regulation-and-deregulation-of-industry, #united-states-politics-and-government, #vaccination-and-immunization