Beneath a Covid Vaccine Debacle, 30 Years of Government Culpability

Washington has rejected plans to revamp vaccine preparedness for decades and repeatedly paid a price. The Biden administration is at a similar crossroads.

#anthrax, #astrazeneca-plc, #biden-joseph-r-jr, #biological-and-chemical-warfare, #biomedical-advanced-research-and-development-authority, #botulism, #coronavirus-2019-ncov, #defense-department, #drugs-pharmaceuticals, #el-hibri-fuad, #emergent-biosolutions-inc, #epidemics, #food-and-drug-administration, #gaithersburg-md, #government-contracts-and-procurement, #johnsonjohnson, #moderna-inc, #politics-and-government, #public-private-sector-cooperation, #smallpox, #stockpiling, #united-states, #vaccination-and-immunization

Moderna Says Its Booster Significantly Raises Antibodies Against Omicron

A 50-microgram dose increased antibodies by roughly 37-fold, and a full dose of 100 micrograms was even more powerful, the company said.

#antibodies, #coronavirus-2019-ncov, #coronavirus-omicron-variant, #moderna-inc, #vaccination-and-immunization

As Omicron Worries Revive, Stocks and Oil Fall

Wall Street’s unease continued after Moderna’s chief executive said there could be a “material drop” in the effectiveness of current vaccines against the new variant.

#bancel-stephane, #coronavirus-2019-ncov, #coronavirus-omicron-variant, #moderna-inc, #stocks-and-bonds

We Got a Head Start on Omicron, So Let’s Not Blow It

South Africa gave the world an early warning. Decisive action on containment and surveillance could help us control it.

#biden-joseph-r-jr, #coronavirus-2019-ncov, #coronavirus-delta-variant, #moderna-inc, #pfizer-inc, #quarantines, #travel-warnings, #vaccination-and-immunization

F.D.A. Authorizes Coronavirus Booster Shots for All Adults

If the C.D.C. agrees, adults who received a second shot of the Pfizer or Moderna vaccine at least six months ago could be eligible by this weekend.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #moderna-inc, #pfizer-inc, #united-states-politics-and-government, #vaccination-and-immunization

Biden Administration Plans to Expand Covid Vaccine Production

The Biden administration will spend billions of dollars on a new plan to combat the pandemic, investing in antiviral pills, rapid tests and manufacturing.

#american-rescue-plan-2021, #biden-joseph-r-jr, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #factories-and-manufacturing, #moderna-inc, #pfizer-inc, #united-states-politics-and-government, #vaccination-and-immunization

Moderna and U.S. at Odds Over Vaccine Patent Rights

Moderna’s patent application names several employees as the sole inventors of a crucial component of its coronavirus vaccine, excluding three government scientists.

#bancel-stephane, #corbett-kizzmekia-s, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #graham-barney-s-1953, #inventions-and-patents, #mascola-john-r, #moderna-inc, #national-institutes-of-health, #patent-and-trademark-office-us, #research, #science-and-technology, #vaccination-and-immunization

Covid-19 and Children: How Often Do Vaccines Cause Heart Problems?

The latest data is reassuring. Myocarditis remains very uncommon, and it is almost always mild and temporary. The heart risk from Covid-19 itself is far greater.

#biontech-se, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #food-and-drug-administration, #heart, #moderna-inc, #pfizer-inc, #teenagers-and-adolescence, #united-states, #vaccination-and-immunization, #your-feed-science

Moderna to Sell Up to 110 Million Covid Vaccine Doses to African Countries

Moderna’s shots have previously gone almost entirely to wealthier countries.

#africa, #african-union, #coronavirus-2019-ncov, #moderna-inc, #vaccination-and-immunization

Moderna Says Vaccine Produces Powerful Immune Response in Those 6 Through 11

The results were announced a day before an advisory committee of the Food and Drug Administration is scheduled to review data for the Pfizer-BioNTech vaccine in children 5 through 11.

#children-and-childhood, #coronavirus-2019-ncov, #moderna-inc, #vaccination-and-immunization

Are Vaccine Boosters Widely Needed? Some Federal Advisers Have Misgivings.

“In our hearts, I think people don’t quite agree with this notion of a booster dose,” said one leading vaccine expert.

#advisory-committee-on-immunization-practices, #biontech-se, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #pfizer-inc, #vaccination-and-immunization, #your-feed-science

C.D.C. Recommends Covid Booster Shots for Millions of Americans

Recipients of the Moderna and the J.&J. vaccines may receive extra doses, although the shots continue to prevent illness and death.

#advisory-committee-on-immunization-practices, #biontech-se, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #disease-rates, #immune-system, #johnsonjohnson, #moderna-inc, #pfizer-inc, #united-states-politics-and-government, #vaccination-and-immunization, #your-feed-science

F.D.A. Authorizes Moderna and Johnson & Johnson Booster Shots

The agency will also allow vaccine recipients to pick which vaccine they want as a booster, endorsing a mix-and-match approach.

#biontech-se, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #pfizer-inc, #united-states-politics-and-government, #vaccination-and-immunization

Mix-and-Match Covid Boosters: Why They Just Might Work

The F.D.A. may authorize booster shots of vaccines different from the ones that Americans originally received. The science behind the move is promising.

#antibodies, #clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #immune-system, #johnsonjohnson, #moderna-inc, #pfizer-inc, #vaccination-and-immunization

F.D.A. to Allow ‘Mix and Match’ Approach for Covid Booster Shots

The agency may act this week, when it is expected to authorize booster shots for recipients of the Moderna and Johnson & Johnson vaccines.

#centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #national-institutes-of-health, #pfizer-inc, #regulation-and-deregulation-of-industry, #united-states-politics-and-government, #vaccination-and-immunization

F.D.A. Panel Unanimously Recommends Johnson & Johnson Booster Shots

But many panel members said J. & J. recipients might also benefit from the option of a Pfizer-BioNTech or Moderna booster, an action that an F.D.A. official said was possible.

#centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #pfizer-inc, #regulation-and-deregulation-of-industry, #vaccination-and-immunization

Where Things Stand on Boosters for Three Vaccines in the U.S.

Confused about who can get a booster shot of which vaccine, and what the F.D.A.’s advisers on vaccines are voting on this week? This scorecard may help.

#biontech-se, #coronavirus-2019-ncov, #disease-rates, #drugs-pharmaceuticals, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #pfizer-inc, #regulation-and-deregulation-of-industry, #vaccination-and-immunization

F.D.A. Panel Recommends Moderna Booster for Certain Groups

Those eligible for the extra shot would include adults over 65 and others at high risk — the same groups now eligible for a Pfizer-BioNTech boost

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #moderna-inc, #vaccination-and-immunization

Data from Federal Scientists Raise Questions About J.&J. Booster Shots

People who have received the company’s one-shot vaccine may benefit from a booster with another brand. F.D.A. advisers will discuss the data on Friday.

#clinical-trials, #coronavirus-2019-ncov, #coronavirus-delta-variant, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #national-institutes-of-health, #pfizer-inc, #research, #united-states-politics-and-government, #vaccination-and-immunization, #your-feed-healthcare

Should Gifted Students Be in Separate Classes?

The debate over gifted-and-talented programs. Also: Moderna’s chairman responds; “illiberal democracy” in Hungary – and the U.S.?

#coronavirus-2019-ncov, #de-blasio-bill, #education-k-12, #gifted-students, #hungary, #moderna-inc, #new-york-city, #orban-viktor, #united-states-politics-and-government, #vaccination-and-immunization

Moderna, Racing for Profits, Keeps Covid Vaccine Out of Reach of Poor

Some poorer countries are paying more and waiting longer for the company’s vaccine than the wealthy — if they have access at all.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #government-contracts-and-procurement, #income-inequality, #johnsonjohnson, #moderna-inc, #pfizer-inc, #third-world-and-developing-countries, #vaccination-and-immunization

Moderna vs. Pfizer: Both Knockouts, but One Seems to Have the Edge

A series of studies found that the Moderna vaccine seemed to be more protective over the long term than the Pfizer-BioNTech vaccine. Here’s why.

#biontech-se, #clinical-trials, #coronavirus-2019-ncov, #immune-system, #johnsonjohnson, #journal-of-the-american-medical-assn, #moderna-inc, #pfizer-inc, #united-states, #vaccination-and-immunization, #your-feed-science

Pressure Grows on U.S. Companies to Share Covid Vaccine Technology

Moderna accepted $2.5 billion in taxpayer money to develop its Covid-19 vaccine. But officials in the U.S. and overseas are having trouble persuading the company to license its technology.

#africa, #biden-joseph-r-jr, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #factories-and-manufacturing, #intellectual-property, #moderna-inc, #pfizer-inc, #public-private-sector-cooperation, #vaccination-and-immunization

Covid Vaccine Prompts Strong Immune Response in Younger Children, Pfizer Says

Vaccinated kids aged 5 to 11 showed evidence of protection against the virus, the company said. The data must be reviewed by the F.D.A. before children can be inoculated.

#biontech-se, #children-and-childhood, #coronavirus-2019-ncov, #disease-rates, #education-k-12, #masks, #moderna-inc, #pfizer-inc, #united-states, #vaccination-and-immunization, #your-feed-science

F.D.A. Panel Recommends Pfizer Boosters for Those Over 65 or at Risk

The committee said there was insufficient evidence to recommend third shots for all adult recipients of the vaccine, as Pfizer had requested.

#centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #food-and-drug-administration, #moderna-inc, #national-institutes-of-health, #pfizer-inc, #united-states, #united-states-politics-and-government, #vaccination-and-immunization

U.S. Booster Policy Is in Flux as Studies Add to Dissent

A week before President Biden’s plan is to roll out, scientists are at odds about whether extra coronavirus shots are needed and for whom.

#biden-joseph-r-jr, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #coronavirus-delta-variant, #disease-rates, #food-and-drug-administration, #israel, #moderna-inc, #pfizer-inc, #regulation-and-deregulation-of-industry, #united-states-politics-and-government, #vaccination-and-immunization

In Review, Top F.D.A. Scientists Question Imminent Need for Booster Shots

An article, written with other vaccine experts, put the regulators at odds with key federal health officials, including Dr. Anthony S. Fauci.

#coronavirus-2019-ncov, #coronavirus-delta-variant, #fauci-anthony-s, #food-and-drug-administration, #gruber-marion, #krause-philip-r, #lancet-the-journal, #marks-peter, #moderna-inc, #pfizer-inc, #regulation-and-deregulation-of-industry, #vaccination-and-immunization, #woodcock-janet, #world-health-organization

Are Covid Booster Shots Really Necessary?

As rich countries ponder the marginal utility of third doses, billions of people around the world are still waiting for their first.

#biden-joseph-r-jr, #biontech-se, #coronavirus-2019-ncov, #debatable, #moderna-inc, #pfizer-inc, #vaccination-and-immunization, #world-health-organization

Health Officials Advise White House to Scale Back Booster Plan for Now

Federal regulators warned on Thursday they may not have enough data to recommend boosters for anyone except certain recipients of the Pfizer vaccine by late September.

#centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #national-institutes-of-health, #pfizer-inc, #united-states-politics-and-government, #vaccination-and-immunization

Stocks Shake Off Bad News to Rally for Seventh Straight Month

With expectations that interest rates will stay down and government spending will stay up, the stock market has learned to live with the pandemic, even as cases increase.

#coronavirus-2019-ncov, #coronavirus-delta-variant, #federal-reserve-system, #interest-rates, #moderna-inc, #powell-jerome-h, #quantitative-easing, #stocks-and-bonds, #united-states-economy

Biden Floats Faster Access to Vaccine Booster Shots

The White House played down the president’s remarks, saying the administration had not changed its original proposal to administer a third shot to most vaccinated adults eight months after the second.

#biden-joseph-r-jr, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #food-and-drug-administration, #israel, #moderna-inc, #pfizer-inc, #united-states-politics-and-government, #vaccination-and-immunization

Biden Falls Short on Pledge for U.S. to Be the World’s Vaccine ‘Arsenal,’ Experts Say

Congress appropriated $16 billion to ramp up Covid-19 countermeasures, but a new report found that the Biden administration had spent very little of it on expanding vaccine manufacturing capacity.

#american-rescue-plan-2021, #biden-joseph-r-jr, #biontech-se, #coronavirus-2019-ncov, #covax, #drugs-pharmaceuticals, #johnsonjohnson, #moderna-inc, #novavax-inc, #pfizer-inc, #united-states-politics-and-government, #vaccination-and-immunization

What to Know About Boosters if You Got the Johnson & Johnson Vaccine

Health experts say that boosters are likely to be needed eventually and that more data should be available in the next several weeks.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #johnsonjohnson, #moderna-inc, #murthy-vivek-h, #pfizer-inc, #south-africa, #united-states, #vaccination-and-immunization, #your-feed-health

Vaccine Effectiveness Against Infection May Wane, C.D.C. Studies Find

Federal health officials said the new data justified a campaign of booster shots. But some scientists disagreed, saying not every American needs another dose.

#centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #coronavirus-delta-variant, #disease-rates, #immune-system, #moderna-inc, #new-york-state, #nursing-homes, #pfizer-inc, #united-states, #vaccination-and-immunization, #your-feed-science

Israel, Once the Model for Beating Covid, Faces New Surge of Infections

One of the most vaccinated societies, Israel now has one of the highest infection rates in the world, raising questions about the vaccine’s efficacy.

#biontech-se, #coronavirus-2019-ncov, #coronavirus-delta-variant, #disease-rates, #israel, #masks, #moderna-inc, #pfizer-inc, #politics-and-government, #tel-aviv-israel, #united-states, #vaccination-and-immunization, #world-health-organization

US to Advise Booster Shots for Most Americans 8 Months After Vaccination

Nursing home residents and health care workers will most likely be the first to get booster shots, as soon as September, followed by other older people who were vaccinated last winter.

#biden-joseph-r-jr, #biontech-se, #coronavirus-2019-ncov, #coronavirus-delta-variant, #food-and-drug-administration, #moderna-inc, #pfizer-inc, #united-states, #united-states-politics-and-government, #vaccination-and-immunization

F.D.A. Aims to Give Final Approval to Pfizer Vaccine by Early Next Month

The Food and Drug Administration’s move is expected to kick off more vaccination mandates for hospital workers, college students and federal troops.

#biontech-se, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #pfizer-inc, #united-states-politics-and-government, #vaccination-and-immunization

We’re Kidding Ourselves That Workers Perform Well From Home

My office reopened at the height of the pandemic. We’ve thrived.

#coronavirus-2019-ncov, #coronavirus-reopenings, #legal-profession, #moderna-inc, #telecommuting

Biden Officials Now Expect Vulnerable Americans to Need Booster Shots

The growing consensus that at least some Americans will need a booster is partly tied to research suggesting that Pfizer’s vaccine is less effective after about six months.

#centers-for-disease-control-and-prevention, #clinical-trials, #coronavirus-2019-ncov, #food-and-drug-administration, #johnsonjohnson, #moderna-inc, #offit-paul-a, #pfizer-inc, #vaccination-and-immunization

J.&J. Vaccine May Be Less Effective Against Delta, Study Suggests

Many who received the shot may need to consider boosters, the authors said. But federal health officials do not recommend second doses.

#astrazeneca-plc, #blood-clots, #coronavirus-2019-ncov, #disease-rates, #drugs-pharmaceuticals, #food-and-drug-administration, #immune-system, #johnsonjohnson, #moderna-inc, #pfizer-inc, #research, #vaccination-and-immunization, #your-feed-science

Should People With Immune Problems Get Third Vaccine Doses?

France is handing out third shots of the two-dose vaccines to cancer patients and others with immune system impairments. In the United States, patients like these are on their own.

#antibodies, #clinical-trials, #coronavirus-2019-ncov, #disease-rates, #drugs-pharmaceuticals, #france, #immune-system, #influenza, #moderna-inc, #research, #transplants, #united-states, #vaccination-and-immunization, #your-feed-science

Johnson & Johnson Vaccine Protects Against Delta Variant, Company Reports

The vaccine also produced long-lasting immune responses, researchers said. Booster shots seem unnecessary, at least for now.

#clinical-trials, #coronavirus-2019-ncov, #immune-system, #johnsonjohnson, #moderna-inc, #pfizer-inc, #united-states, #vaccination-and-immunization, #your-feed-science

Behind Biden’s Pledge to Share 80 Million Vaccine Doses

A shipment to Pakistan was part of a new phase of the administration’s pandemic response: a round-the-clock effort to clear regulatory and logistical hurdles to share doses with countries in need.

#biden-joseph-r-jr, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #covax, #moderna-inc, #pakistan, #state-department, #united-states-international-relations, #united-states-politics-and-government, #vaccination-and-immunization

Three Studies, One Result: Vaccines Point the Way Out of the Pandemic

New scientific research underscores the effectiveness of vaccines and their versatility in the fight against the coronavirus.

#antibodies, #astrazeneca-plc, #biontech-se, #clinical-trials, #coronavirus-2019-ncov, #disease-rates, #immune-system, #johnsonjohnson, #moderna-inc, #nature-journal, #pfizer-inc, #research, #united-states, #vaccination-and-immunization, #your-feed-science

Pfizer and Moderna Vaccines Likely to Produce Lasting Immunity, Study Finds

Immune cells are still organizing to fight the coronavirus months after inoculation, scientists reported.

#antibodies, #biontech-se, #coronavirus-2019-ncov, #immune-system, #lymph-nodes-and-lymphatic-system, #moderna-inc, #nature-journal, #pfizer-inc, #vaccination-and-immunization, #your-feed-science

Why More People Are Getting Two Different Coronavirus Vaccines

Several countries are allowing mix-and-match inoculation, which scientists hope will have benefits, and Chancellor Angela Merkel of Germany is among those to get it.

#astrazeneca-plc, #clinical-trials, #coronavirus-2019-ncov, #merkel-angela, #moderna-inc, #novavax-inc, #oxford-university, #pfizer-inc, #vaccination-and-immunization

Immunity to the Coronavirus May Persist for Years, Scientists Find

Important immune cells survive in the bone marrow of people who were infected with the virus or were inoculated against it, new research suggests.

#antibodies, #bone-marrow, #coronavirus-2019-ncov, #immune-system, #moderna-inc, #nature-journal, #vaccination-and-immunization, #your-feed-science

Moderna Vaccine Highly Effective in Adolescents, Company Says

The U.S., which has a surplus of vaccines, could soon have two options for teens while many countries face shortages.

#children-and-childhood, #clinical-trials, #coronavirus-2019-ncov, #moderna-inc, #teenagers-and-adolescence, #vaccination-and-immunization, #your-feed-health, #your-feed-science

Covid Vaccines Are Now on Wheels

Mobile Covid-19 vaccine clinics in vans and buses are rolling up to neighborhoods in Delaware, Minnesota and Washington State to reach people who have been unable to travel to vaccination centers.

#delaware, #disease-rates, #johnsonjohnson, #minnesota, #moderna-inc, #vaccination-and-immunization, #washington-state

Taiwan Faces a Surge in New Covid-19 Infections

The island’s border controls had shielded it from the worst of the pandemic. But new variants and a slow vaccine rollout gave the virus an opening.

#academia-sinica, #astrazeneca-plc, #chen-shih-chung, #china-airlines, #coronavirus-2019-ncov, #coronavirus-risks-and-safety-concerns, #moderna-inc, #taipei-taiwan, #taiwan, #vaccination-and-immunization