Anthony Fauci on the Lab Leak Theory and Emailing Mark Zuckerberg

America’s chief immunologist claps back.

#audio-neutral-informative, #coronavirus-2019-ncov, #fauci-anthony-s, #national-institutes-of-health, #vaccination-and-immunization

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A Pill to Treat Covid-19? The U.S. Is Betting on It.

A new $3.2 billion program will support the development of antiviral pills, which could start arriving by the end of this year.

#clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #national-institutes-of-health, #remdesivir-drug, #your-feed-healthcare

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Scientists Report Earliest Known Coronavirus Cases in Five US States

Blood drawn from nine people in the earliest days of the pandemic tested positive for the infection. But some experts questioned the results.

#antibodies, #blood-donation, #china, #clinical-infectious-diseases-journal, #coronavirus-2019-ncov, #disease-rates, #illinois, #massachusetts, #mississippi, #national-institutes-of-health, #pennsylvania, #states-us, #united-states, #wisconsin, #your-feed-science

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Scientists Report Earliest Known Coronavirus Infections in Five U.S. States

Blood drawn from nine people in the earliest days of the pandemic tested positive for the infection. But some experts questioned the results.

#antibodies, #blood-donation, #china, #clinical-infectious-diseases-journal, #coronavirus-2019-ncov, #disease-rates, #illinois, #massachusetts, #mississippi, #national-institutes-of-health, #pennsylvania, #states-us, #united-states, #wisconsin, #your-feed-science

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These Sisters With Sickle Cell Had Devastating — and Preventable — Strokes

Kyra and Kami never got a simple test that could have protected them. Their story exemplifies the failure to care for people with the disease, most of whom are Black.

#black-people, #children-and-childhood, #doctors, #genetics-and-heredity, #national-institutes-of-health, #preventive-medicine, #race-and-ethnicity, #sickle-cell-anemia, #stroke, #tests-medical, #transfusions, #ultrasonic-imaging-and-sonograms

0

America’s Next Move? Vaccinate the World.

Vaccinating the world is possible. The United States should lead the way. 

#biden-joseph-r-jr, #coronavirus-2019-ncov, #national-institutes-of-health, #united-states, #vaccination-and-immunization, #world-health-organization

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C.D.C. Chief Defends Pandemic Guidance as Impatience Mounts

At a Senate hearing on the federal government’s pandemic response, Republicans criticized the government’s guidance for cruise ships, fishermen, summer camps and outdoor mask wearing.

#centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #coronavirus-reopenings, #coronavirus-risks-and-safety-concerns, #disease-rates, #national-institutes-of-health, #united-states-politics-and-government, #vaccination-and-immunization

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Biden proposes ARPA-H, a health research agency to ‘end cancer’ modeled after DARPA

In a joint address to Congress last night, President Biden updated the nation on vaccination efforts and outlined his administration’s ambitious goals.

Biden’s first 100 days have been characterized by sweeping legislative packages that could lift millions of Americans out of poverty and slow the clock on the climate crisis, but during his first joint address to Congress, the president highlighted another smaller plan that’s no less ambitious: to “end cancer as we know it.”

“I can think of no more worthy investment,” Biden said Wednesday night. “I know of nothing that is more bipartisan…. It’s within our power to do it.”

The comments weren’t out of the blue. Earlier this month, the White House released a budget request for $6.5 billion to launch a new government agency for breakthrough health research. The proposed health agency would be called ARPA-H and would live within the NIH. The initial focus would be on cancer, diabetes and Alzheimer’s but the agency would also pursue other “transformational innovation” that could remake health research.

The $6.5 billion investment is a piece of the full $51 billion NIH budget. But some critics believe that ARPA-H should sit under the Department of Health and Human Services rather than being nested under NIH. 

ARPA-H would be modeled after the Defense Advanced Research Projects Agency (DARPA), which develops moonshot-like tech for defense applications. DARPA’s goals often sound more like science fiction than science, but the agency contributed to or created a number of now ubiquitous technologies, including a predecessor to GPS and most famously ARPANET, the computer network that grew into the modern internet.

Unlike more conservative, incremental research teams, DARPA aggressively pursues major scientific advances in a way that shares more in common with Silicon Valley than it does with other governmental agencies. Biden believes that using the DARPA model on cutting edge health research would keep the U.S. from lagging behind in biotech.

“China and other countries are closing in fast,” Biden said during the address. “We have to develop and dominate the products and technologies of the future: advanced batteries, biotechnology, computer chips, and clean energy.”

#arpanet, #biden, #biotechnology, #cancer, #congress, #darpa, #diabetes, #government, #health, #joe-biden, #life-sciences, #national-institute-of-health, #national-institutes-of-health, #president, #tc, #united-states, #white-house

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Biden Administration Ends Limit on Fetal Tissue Research

The decision reverses Trump administration rules and allows scientists to use tissue derived from elective abortions to develop treatments for diseases including cancer and AIDS.

#abortion, #coronavirus-2019-ncov, #fetal-tissue, #health-and-human-services-department, #international-society-for-stem-cell-research, #national-institutes-of-health, #research, #science-and-technology, #tissue-human, #trump-donald-j, #vaccination-and-immunization, #your-feed-science

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Biden Administration Ends Limits on Use of Fetal Tissue for Research

The decision reverses Trump administration rules and allows scientists to use tissue derived from elective abortions to develop treatments for diseases including cancer and AIDS.

#abortion, #coronavirus-2019-ncov, #fetal-tissue, #health-and-human-services-department, #international-society-for-stem-cell-research, #national-institutes-of-health, #research, #science-and-technology, #tissue-human, #trump-donald-j, #vaccination-and-immunization, #your-feed-science

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Joe Biden Made a Promise to Scientists. He Can Still Keep It.

Researchers who receive federal help consistently fail to report their results to the public. The government should hold them accountable.

#clinical-trials, #drugs-pharmaceuticals, #national-institutes-of-health, #research

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Drug Prices Are High Thanks to Research That Americans Pay For

The pharmaceutical industry doesn’t want things to change, but Americans can have both lower prices and innovation.

#coronavirus-2019-ncov, #defense-advanced-research-projects-agency, #drugs-pharmaceuticals, #national-institutes-of-health, #prices-fares-fees-and-rates, #research, #vaccination-and-immunization

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Rich Countries Signed Away a Chance to Vaccinate the World

Despite warnings, American and European officials gave up leverage that could have guaranteed access for billions of people. That risks prolonging the pandemic.

#astrazeneca-plc, #biontech-se, #coronavirus-2019-ncov, #gamaleya-research-institute-of-epidemiology-and-microbiology, #graham-barney-s-1953, #intellectual-property, #inventions-and-patents, #moderna-inc, #national-institutes-of-health, #politics-and-government, #slaoui-moncef-m, #vaccination-and-immunization

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Long Covid is a Looming Health Crisis

Lingering symptoms from the coronavirus may turn out to be one of the largest mass disabling events in modern history.

#chronic-condition-health, #chronic-fatigue-syndrome, #coronavirus-2019-ncov, #coronavirus-risks-and-safety-concerns, #disabilities, #disability-insurance, #national-institutes-of-health, #research, #vaccination-and-immunization

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Future Vaccines Depend on Test Subjects in Short Supply: Monkeys

The pandemic has highlighted the United States’ dependence on China for research animals, reviving calls for a “strategic monkey reserve.”

#animal-abuse-rights-and-welfare, #china, #coronavirus-2019-ncov, #international-trade-and-world-market, #monkeys-and-apes, #national-institutes-of-health, #research, #vaccination-and-immunization

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With More Vaccines Secured, Biden Warns of Hurdles to Come

The Biden administration has secured more coronavirus vaccines, but the president struck a cautious tone about logistical issues that could keep some Americans from being vaccinated.

#biden-joseph-r-jr, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #national-institutes-of-health, #trump-donald-j, #united-states-politics-and-government, #vaccination-and-immunization

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Emil Freireich, Groundbreaking Cancer Researcher, Dies at 93

He helped devise a successful chemotherapy regimen for childhood leukemia, which had long been a death sentence.

#blood-donation, #cancer, #deaths-obituaries, #frei-emil-iii-1924-2013, #freireich-emil, #leukemia, #national-cancer-institute, #national-institutes-of-health, #university-of-texas-m-d-anderson-cancer-center

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Governments Sign Secret Vaccine Deals: Here’s What They Hide

Multibillion-dollar contracts give drug makers liability shields, patent ownership and leeway on delivery dates and pricing — and promises that much of it will not be made public.

#astrazeneca-plc, #coalition-for-epidemic-preparedness-innovations, #coronavirus-2019-ncov, #government-contracts-and-procurement, #moderna-inc, #national-institutes-of-health, #novavax-inc, #pfizer-inc, #vaccination-and-immunization, #world-health-organization

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Biden Advisers Say U.S. Will Remain Vulnerable to Covid Unless Congress Acts

In pleas for more money from Capitol Hill, the advisers said the United States was still facing shortages of protective gear and other supplies.

#biden-joseph-r-jr, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #fauci-anthony-s, #national-institutes-of-health, #united-states-politics-and-government, #vaccination-and-immunization, #walensky-rochelle, #war-and-emergency-powers-us, #zients-jeffrey-d

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Millions Meant for Public Health Threats Were Diverted Elsewhere, Watchdog Says

The money went to unrelated government activities like the removal of office furniture, news subscriptions and legal expenses.

#biden-joseph-r-jr, #bright-rick-a, #coronavirus-2019-ncov, #kadlec-robert-p, #national-institutes-of-health, #united-states-politics-and-government

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Warning of Shortages, Researchers Look to Stretch Vaccine Supply

The N.I.H. and Moderna are examining whether doses of Moderna’s coronavirus vaccine can be halved to double the supply, while scientists look for other ways to extend availability.

#clinical-trials, #coronavirus-2019-ncov, #fauci-anthony-s, #moderna-inc, #national-institutes-of-health, #pfizer-inc, #research, #shortages

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‘Covid, Covid, Covid’: In Trump’s Final Chapter, a Failure to Rise to the Moment

As the U.S. confronted a new wave of infection and death through the summer and fall, the president’s approach to the pandemic came down to a single question: What would it mean for him?

#atlas-scott-w, #birx-deborah-l, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #fauci-anthony-s, #food-and-drug-administration, #hahn-stephen-m-1960, #health-and-human-services-department, #kushner-jared, #masks, #meadows-mark-r-1959, #national-institutes-of-health, #pence-mike, #presidential-election-of-2020, #trump-donald-j, #united-states-politics-and-government, #vaccination-and-immunization

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Trial of High-Dose Blood Thinners in I.C.U. Coronavirus Patients Is Halted

Giving anticoagulants to hospitalized Covid-19 patients is routine. But high doses may sometimes do more harm than good, a safety board finds.

#blood-clots, #clinical-trials, #coronavirus-2019-ncov, #journal-of-the-american-college-of-cardiology, #national-institutes-of-health, #new-york-university, #university-of-pittsburgh-medical-center, #your-feed-healthcare

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The Covid-19 Vaccine Doesn’t Mean Big Pharma Is Your Savior

Heroic work went into the development of the coronavirus vaccines. But that doesn’t mean this industry deserves your affection.

#astrazeneca-plc, #biotechnology-and-bioengineering, #centers-for-disease-control-and-prevention, #clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #moderna-inc, #national-institutes-of-health, #oxford-university, #pfizer-inc, #public-private-sector-cooperation, #vaccination-and-immunization

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Moderna Vaccine Is Highly Protective and Prevents Severe Covid, Data Show

The positive review likely ensures that the F.D.A. will grant emergency authorization for a second coronavirus vaccine this week for millions of Americans.

#astrazeneca-plc, #clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #moderna-inc, #national-institutes-of-health, #united-states-politics-and-government, #your-feed-healthcare

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How the US, UK and Canada Will Roll Out the Covid Vaccine

Within days, all three countries could be giving the Pfizer-BioNTech vaccine, but they have varying strategies and challenges. The U.S. plan, working through the states, is the least centralized.

#astrazeneca-plc, #coronavirus-2019-ncov, #european-union, #great-britain, #moderna-inc, #national-health-service, #national-institutes-of-health, #oxford-university, #pfizer-inc, #united-states, #vaccination-and-immunization

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The First Covid Vaccine Will Not Make Life Normal Again

Come spring, Americans may have their choice of several so-so coronavirus vaccines — with no way of knowing which one is best.

#clinical-trials, #coronavirus-2019-ncov, #coronavirus-risks-and-safety-concerns, #food-and-drug-administration, #national-institutes-of-health, #placebos, #public-private-sector-cooperation, #research, #united-states-politics-and-government, #vaccination-and-immunization, #your-feed-healthcare, #your-feed-science

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Whistle-Blowing Scientist Quits Government With Final Broadside

Dr. Rick Bright, who said he was demoted at the health department for blowing the whistle on a politicized coronavirus response, remains concerned about White House interference.

#biomedical-advanced-research-and-development-authority, #bright-rick-a, #coronavirus-2019-ncov, #health-and-human-services-department, #masks, #national-institutes-of-health, #tests-medical, #united-states-politics-and-government

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U.S. Lab Chimps Stuck in Retirement Limbo

Activists and some congressional lawmakers are demanding that the N.I.H. reconsider its refusal to move 39 chimpanzees from a research center to a sanctuary.

#alamogordo-primate-facility, #animal-abuse-rights-and-welfare, #animal-behavior, #chimp-haven, #collins-francis-s, #monkeys-and-apes, #national-institutes-of-health, #research, #your-feed-science

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N.I.H. Official Departs After Anonymous Posts Attacking Public Health Leaders

A managing editor of the right-wing website RedState appeared to attack Dr. Anthony S. Fauci and spread misinformation about the coronavirus pandemic while working for Dr. Fauci’s agency.

#conspiracy-theories, #coronavirus-2019-ncov, #crews-william-b, #fauci-anthony-s, #health-and-human-services-department, #masks, #medicine-and-health, #national-institutes-of-health, #redstate-blog, #rumors-and-misinformation, #trump-donald-j, #united-states-politics-and-government

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Eli Lilly Claims Experimental Drug Protects Covid-19 Patients

A so-called monoclonal antibody lowered levels of the coronavirus and prevented hospitalizations. The research has not yet been vetted by independent experts.

#antibodies, #clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #eli-lilly-and-company, #national-institutes-of-health, #united-states

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Trump Pressed for a Plasma Treatment. Officials Worry, Is a Vaccine Next?

New details of how the president has demanded faster action from health agencies help explain the intensifying concern that he could demand pre-Election Day approval of a vaccine.

#azar-alex-m-ii, #birx-deborah-l, #blood, #clinical-trials, #collins-francis-s, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #hahn-stephen-m-1960, #health-and-human-services-department, #kushner-jared, #marks-peter, #mayo-clinic, #meadows-mark-r-1959, #national-institutes-of-health, #presidential-election-of-2020, #republican-national-convention, #trump-donald-j, #united-states-politics-and-government, #vaccination-and-immunization

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Backed by Federal Funds, New Virus Tests Are Hitting the Market

Six months into the pandemic and with no coherent national testing strategy, the Trump administration is encouraging private development of an array of faster and cheaper techniques.

#abbott-laboratories, #budgets-and-budgeting, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #fluidigm, #food-and-drug-administration, #giroir-brett-p, #health-and-human-services-department, #national-institutes-of-health, #quidel-corporation, #regulation-and-deregulation-of-industry, #tests-medical, #trump-donald-j, #united-states-politics-and-government

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American Clinical Research Needs to Step Up Its Game Against Covid-19

Here’s how: Follow Britain’s example.

#clinical-trials, #coronavirus-2019-ncov, #food-and-drug-administration, #great-britain, #national-health-service, #national-institutes-of-health, #research, #united-states

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The F.D.A. Commissioner’s Fuzzy Math

Stephen Hahn made misleading remarks about a coronavirus treatment. How did that happen?

#coronavirus-2019-ncov, #food-and-drug-administration, #hahn-stephen-m-1960, #national-institutes-of-health, #united-states, #vaccination-and-immunization

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An ‘Unprecedented’ Effort to Stop the Coronavirus in Nursing Homes

Researchers are testing an experimental drug to halt sudden outbreaks. The trial may bring a new type of treatment for the virus.

#antibodies, #clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #elderly, #eli-lilly-and-company, #illinois, #national-institutes-of-health, #nursing-homes, #tests-medical, #your-feed-healthcare

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Trump Ethics Panel Urges Rejection of Fetal Tissue Research

A new advisory board, appointed by the Trump administration, recommended that the health secretary reject funding for virtually every fetal tissue research project it considered.

#abortion, #azar-alex-m-ii, #conservatism-us-politics, #fetal-tissue, #health-and-human-services-department, #national-institutes-of-health, #research, #trump-donald-j, #united-states-politics-and-government

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Clinical Trials of Coronavirus Drugs Are Taking Longer Than Expected

Antibody trials sponsored by Regeneron and Eli Lilly are off to a slow start because of a dearth of tests, overwhelmed hospitals and reluctant patients.

#clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #eli-lilly-and-company, #emory-university, #hospitals, #national-institutes-of-health, #regeneron-pharmaceuticals-inc, #research, #your-feed-science

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Testing Backlogs May Cloud the True Spread of the Coronavirus

Public health experts say delays in testing continue to hinder attempts to track and contain the spread of disease.

#coronavirus-2019-ncov, #disease-rates, #laboratories-and-scientific-equipment, #national-institutes-of-health, #quarantines, #tests-medical, #united-states, #your-feed-healthcare

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Inside Trump’s Failure: The Rush to Abandon Leadership Role on the Virus

The roots of the nation’s current inability to control the pandemic can be traced to mid-April, when the White House embraced overly rosy projections to proclaim victory and move on.

#birx-deborah-l, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #coronavirus-reopenings, #coronavirus-risks-and-safety-concerns, #disease-rates, #fauci-anthony-s, #health-and-human-services-department, #kushner-jared, #meadows-mark-r-1959, #medicine-and-health, #national-institutes-of-health, #presidential-election-of-2020, #trump-donald-j, #united-states-politics-and-government, #university-of-washington

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Treacherous Times for Dr. Fauci in the Sacred Cow Business

As the Trump White House attacks the government’s top infectious disease expert, “What’s happening to Dr. Fauci?” has become an urgent topic in Washington and in science and medical circles.

#bush-george-w, #coronavirus-2019-ncov, #fauci-anthony-s, #greenspan-alan, #hamburg-margaret-a, #kramer-larry-1935, #lewis-john-r, #mccain-john, #mueller-robert-s-iii, #national-institutes-of-health, #navarro-peter, #powell-colin-l, #trump-donald-j, #usa-today

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Fauci Back at the White House, a Day After Trump Aides Tried to Undermine Him

The visit underscored a reality for both the president and his most prominent coronavirus adviser: They are stuck with each other.

#collins-francis-s, #coronavirus-2019-ncov, #fauci-anthony-s, #hamburg-margaret-a, #health-and-human-services-department, #mcenany-kayleigh, #national-institute-of-allergy-and-infectious-diseases, #national-institutes-of-health, #trump-donald-j, #united-states-politics-and-government

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Will We Be Hostages to Drug Makers’ Covid Vaccine Pricing?

The United States is the only developed nation unable to balance cost, efficacy and social good in setting prices.

#biomedical-advanced-research-and-development-authority, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #health-insurance-and-managed-care, #inventions-and-patents, #medicare, #national-institutes-of-health, #prices-fares-fees-and-rates, #vaccination-and-immunization

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Fraudulent Covid Antibody Tests? FBI Warns of Scammers, Identity Theft

Scammers are out to get personal information that could lead to identity theft.

#centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #coronavirus-aid-relief-and-economic-security-act-2020, #federal-bureau-of-investigation, #federal-trade-commission, #food-and-drug-administration, #frauds-and-swindling, #health-insurance-and-managed-care, #identity-theft, #internal-revenue-service, #medicare, #national-institutes-of-health, #tests-medical

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Dog Breeding in the Neolithic Age

Fossils and modern DNA show the ancient roots of Arctic sled dogs.

#alaska, #arctic-regions, #dna-deoxyribonucleic-acid, #dog-sledding, #dogs, #europe, #genetics-and-heredity, #greenland, #national-institutes-of-health, #siberia, #university-of-california-santa-cruz, #university-of-copenhagen, #wolves, #your-feed-science

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Federal Agency Halts Studies of Hydroxychloroquine, Drug Trump Promoted

The National Institutes of Health decided to stop one trial because the drug was unlikely to benefit patients, and another because not enough people enrolled.

#clinical-trials, #coronavirus-2019-ncov, #hydroxychloroquine-drug, #national-heart-lung-and-blood-institute, #national-institutes-of-health, #trump-donald-j, #united-states-politics-and-government, #your-feed-science

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Coronavirus Attacks the Lungs. A Federal Agency Just Halted Funding for New Lung Treatments.

The shift, quietly disclosed on a government website, highlights how the Trump administration is favoring development of vaccines over treatments for the sickest patients.

#biomedical-advanced-research-and-development-authority, #clinical-trials, #coronavirus-2019-ncov, #dexamethasone-drug, #drugs-pharmaceuticals, #health-and-human-services-department, #lungs, #national-institutes-of-health, #research, #tests-medical, #trump-donald-j, #united-states-politics-and-government, #vaccination-and-immunization, #ventilators-medical, #your-feed-healthcare

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Former D.E.A. Spokesman Pleads Guilty to $4.4 Million Fraud

Garrison Kenneth Courtney pretended to be a C.I.A. officer to bilk companies.

#central-intelligence-agency, #courtney-garrison-kenneth, #drug-enforcement-administration, #espionage-and-intelligence-services, #frauds-and-swindling, #government-contracts-and-procurement, #national-institutes-of-health

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The C.D.C. Waited ‘Its Entire Existence for This Moment.’ What Went Wrong?

The technology was old, the data poor, the bureaucracy slow, the guidance confusing, the administration not in agreement. The coronavirus shook the world’s premier health agency, creating a loss of confidence and hampering the U.S. response to the crisis.

#american-public-health-assn, #atlanta-ga, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #coronavirus-reopenings, #epidemic-intelligence-service, #federal-emergency-management-agency, #food-and-drug-administration, #health-and-human-services-department, #johns-hopkins-university, #national-institutes-of-health, #quarantines, #redfield-robert-r, #tests-medical, #trump-donald-j, #united-states, #united-states-politics-and-government, #world-health-organization

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U.S. and Chinese Scientists Trace Evolution of Coronaviruses in Bats

Researchers whose canceled U.S. grant caused an outcry from other scientists urge preventive monitoring of viruses in southwestern China.

#bats, #china, #coronavirus-2019-ncov, #daszak-peter, #ebright-richard-h, #ecohealth-alliance, #laos, #myanmar, #national-institutes-of-health, #nature-communications-journal, #research, #rutgers-the-state-university-of-new-jersey, #sars-severe-acute-respiratory-syndrome, #southeast-asia, #trump-donald-j, #united-states-politics-and-government, #vietnam, #your-feed-science

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