The First Covid Vaccine Will Not Make Life Normal Again

Come spring, Americans may have their choice of several so-so coronavirus vaccines — with no way of knowing which one is best.

#clinical-trials, #coronavirus-2019-ncov, #coronavirus-risks-and-safety-concerns, #food-and-drug-administration, #national-institutes-of-health, #placebos, #public-private-sector-cooperation, #research, #united-states-politics-and-government, #vaccination-and-immunization, #your-feed-healthcare, #your-feed-science

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Whistle-Blowing Scientist Quits Government With Final Broadside

Dr. Rick Bright, who said he was demoted at the health department for blowing the whistle on a politicized coronavirus response, remains concerned about White House interference.

#biomedical-advanced-research-and-development-authority, #bright-rick-a, #coronavirus-2019-ncov, #health-and-human-services-department, #masks, #national-institutes-of-health, #tests-medical, #united-states-politics-and-government

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U.S. Lab Chimps Stuck in Retirement Limbo

Activists and some congressional lawmakers are demanding that the N.I.H. reconsider its refusal to move 39 chimpanzees from a research center to a sanctuary.

#alamogordo-primate-facility, #animal-abuse-rights-and-welfare, #animal-behavior, #chimp-haven, #collins-francis-s, #monkeys-and-apes, #national-institutes-of-health, #research, #your-feed-science

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N.I.H. Official Departs After Anonymous Posts Attacking Public Health Leaders

A managing editor of the right-wing website RedState appeared to attack Dr. Anthony S. Fauci and spread misinformation about the coronavirus pandemic while working for Dr. Fauci’s agency.

#conspiracy-theories, #coronavirus-2019-ncov, #crews-william-b, #fauci-anthony-s, #health-and-human-services-department, #masks, #medicine-and-health, #national-institutes-of-health, #redstate-blog, #rumors-and-misinformation, #trump-donald-j, #united-states-politics-and-government

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Eli Lilly Claims Experimental Drug Protects Covid-19 Patients

A so-called monoclonal antibody lowered levels of the coronavirus and prevented hospitalizations. The research has not yet been vetted by independent experts.

#antibodies, #clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #eli-lilly-and-company, #national-institutes-of-health, #united-states

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Trump Pressed for a Plasma Treatment. Officials Worry, Is a Vaccine Next?

New details of how the president has demanded faster action from health agencies help explain the intensifying concern that he could demand pre-Election Day approval of a vaccine.

#azar-alex-m-ii, #birx-deborah-l, #blood, #clinical-trials, #collins-francis-s, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #hahn-stephen-m-1960, #health-and-human-services-department, #kushner-jared, #marks-peter, #mayo-clinic, #meadows-mark-r-1959, #national-institutes-of-health, #presidential-election-of-2020, #republican-national-convention, #trump-donald-j, #united-states-politics-and-government, #vaccination-and-immunization

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Backed by Federal Funds, New Virus Tests Are Hitting the Market

Six months into the pandemic and with no coherent national testing strategy, the Trump administration is encouraging private development of an array of faster and cheaper techniques.

#abbott-laboratories, #budgets-and-budgeting, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #fluidigm, #food-and-drug-administration, #giroir-brett-p, #health-and-human-services-department, #national-institutes-of-health, #quidel-corporation, #regulation-and-deregulation-of-industry, #tests-medical, #trump-donald-j, #united-states-politics-and-government

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American Clinical Research Needs to Step Up Its Game Against Covid-19

Here’s how: Follow Britain’s example.

#clinical-trials, #coronavirus-2019-ncov, #food-and-drug-administration, #great-britain, #national-health-service, #national-institutes-of-health, #research, #united-states

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The F.D.A. Commissioner’s Fuzzy Math

Stephen Hahn made misleading remarks about a coronavirus treatment. How did that happen?

#coronavirus-2019-ncov, #food-and-drug-administration, #hahn-stephen-m-1960, #national-institutes-of-health, #united-states, #vaccination-and-immunization

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An ‘Unprecedented’ Effort to Stop the Coronavirus in Nursing Homes

Researchers are testing an experimental drug to halt sudden outbreaks. The trial may bring a new type of treatment for the virus.

#antibodies, #clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #elderly, #eli-lilly-and-company, #illinois, #national-institutes-of-health, #nursing-homes, #tests-medical, #your-feed-healthcare

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Trump Ethics Panel Urges Rejection of Fetal Tissue Research

A new advisory board, appointed by the Trump administration, recommended that the health secretary reject funding for virtually every fetal tissue research project it considered.

#abortion, #azar-alex-m-ii, #conservatism-us-politics, #fetal-tissue, #health-and-human-services-department, #national-institutes-of-health, #research, #trump-donald-j, #united-states-politics-and-government

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Clinical Trials of Coronavirus Drugs Are Taking Longer Than Expected

Antibody trials sponsored by Regeneron and Eli Lilly are off to a slow start because of a dearth of tests, overwhelmed hospitals and reluctant patients.

#clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #eli-lilly-and-company, #emory-university, #hospitals, #national-institutes-of-health, #regeneron-pharmaceuticals-inc, #research, #your-feed-science

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Testing Backlogs May Cloud the True Spread of the Coronavirus

Public health experts say delays in testing continue to hinder attempts to track and contain the spread of disease.

#coronavirus-2019-ncov, #disease-rates, #laboratories-and-scientific-equipment, #national-institutes-of-health, #quarantines, #tests-medical, #united-states, #your-feed-healthcare

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Inside Trump’s Failure: The Rush to Abandon Leadership Role on the Virus

The roots of the nation’s current inability to control the pandemic can be traced to mid-April, when the White House embraced overly rosy projections to proclaim victory and move on.

#birx-deborah-l, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #coronavirus-reopenings, #coronavirus-risks-and-safety-concerns, #disease-rates, #fauci-anthony-s, #health-and-human-services-department, #kushner-jared, #meadows-mark-r-1959, #medicine-and-health, #national-institutes-of-health, #presidential-election-of-2020, #trump-donald-j, #united-states-politics-and-government, #university-of-washington

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Treacherous Times for Dr. Fauci in the Sacred Cow Business

As the Trump White House attacks the government’s top infectious disease expert, “What’s happening to Dr. Fauci?” has become an urgent topic in Washington and in science and medical circles.

#bush-george-w, #coronavirus-2019-ncov, #fauci-anthony-s, #greenspan-alan, #hamburg-margaret-a, #kramer-larry-1935, #lewis-john-r, #mccain-john, #mueller-robert-s-iii, #national-institutes-of-health, #navarro-peter, #powell-colin-l, #trump-donald-j, #usa-today

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Fauci Back at the White House, a Day After Trump Aides Tried to Undermine Him

The visit underscored a reality for both the president and his most prominent coronavirus adviser: They are stuck with each other.

#collins-francis-s, #coronavirus-2019-ncov, #fauci-anthony-s, #hamburg-margaret-a, #health-and-human-services-department, #mcenany-kayleigh, #national-institute-of-allergy-and-infectious-diseases, #national-institutes-of-health, #trump-donald-j, #united-states-politics-and-government

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Will We Be Hostages to Drug Makers’ Covid Vaccine Pricing?

The United States is the only developed nation unable to balance cost, efficacy and social good in setting prices.

#biomedical-advanced-research-and-development-authority, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #health-insurance-and-managed-care, #inventions-and-patents, #medicare, #national-institutes-of-health, #prices-fares-fees-and-rates, #vaccination-and-immunization

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Fraudulent Covid Antibody Tests? FBI Warns of Scammers, Identity Theft

Scammers are out to get personal information that could lead to identity theft.

#centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #coronavirus-aid-relief-and-economic-security-act-2020, #federal-bureau-of-investigation, #federal-trade-commission, #food-and-drug-administration, #frauds-and-swindling, #health-insurance-and-managed-care, #identity-theft, #internal-revenue-service, #medicare, #national-institutes-of-health, #tests-medical

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Dog Breeding in the Neolithic Age

Fossils and modern DNA show the ancient roots of Arctic sled dogs.

#alaska, #arctic-regions, #dna-deoxyribonucleic-acid, #dog-sledding, #dogs, #europe, #genetics-and-heredity, #greenland, #national-institutes-of-health, #siberia, #university-of-california-santa-cruz, #university-of-copenhagen, #wolves, #your-feed-science

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Federal Agency Halts Studies of Hydroxychloroquine, Drug Trump Promoted

The National Institutes of Health decided to stop one trial because the drug was unlikely to benefit patients, and another because not enough people enrolled.

#clinical-trials, #coronavirus-2019-ncov, #hydroxychloroquine-drug, #national-heart-lung-and-blood-institute, #national-institutes-of-health, #trump-donald-j, #united-states-politics-and-government, #your-feed-science

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Coronavirus Attacks the Lungs. A Federal Agency Just Halted Funding for New Lung Treatments.

The shift, quietly disclosed on a government website, highlights how the Trump administration is favoring development of vaccines over treatments for the sickest patients.

#biomedical-advanced-research-and-development-authority, #clinical-trials, #coronavirus-2019-ncov, #dexamethasone-drug, #drugs-pharmaceuticals, #health-and-human-services-department, #lungs, #national-institutes-of-health, #research, #tests-medical, #trump-donald-j, #united-states-politics-and-government, #vaccination-and-immunization, #ventilators-medical, #your-feed-healthcare

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Former D.E.A. Spokesman Pleads Guilty to $4.4 Million Fraud

Garrison Kenneth Courtney pretended to be a C.I.A. officer to bilk companies.

#central-intelligence-agency, #courtney-garrison-kenneth, #drug-enforcement-administration, #espionage-and-intelligence-services, #frauds-and-swindling, #government-contracts-and-procurement, #national-institutes-of-health

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The C.D.C. Waited ‘Its Entire Existence for This Moment.’ What Went Wrong?

The technology was old, the data poor, the bureaucracy slow, the guidance confusing, the administration not in agreement. The coronavirus shook the world’s premier health agency, creating a loss of confidence and hampering the U.S. response to the crisis.

#american-public-health-assn, #atlanta-ga, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #coronavirus-reopenings, #epidemic-intelligence-service, #federal-emergency-management-agency, #food-and-drug-administration, #health-and-human-services-department, #johns-hopkins-university, #national-institutes-of-health, #quarantines, #redfield-robert-r, #tests-medical, #trump-donald-j, #united-states, #united-states-politics-and-government, #world-health-organization

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U.S. and Chinese Scientists Trace Evolution of Coronaviruses in Bats

Researchers whose canceled U.S. grant caused an outcry from other scientists urge preventive monitoring of viruses in southwestern China.

#bats, #china, #coronavirus-2019-ncov, #daszak-peter, #ebright-richard-h, #ecohealth-alliance, #laos, #myanmar, #national-institutes-of-health, #nature-communications-journal, #research, #rutgers-the-state-university-of-new-jersey, #sars-severe-acute-respiratory-syndrome, #southeast-asia, #trump-donald-j, #united-states-politics-and-government, #vietnam, #your-feed-science

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We Need a Voice for Public Health in the President’s Cabinet

It’s the best way to get the resources and health system we need.

#centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #epidemics, #health-and-human-services-department, #health-insurance-and-managed-care, #medicine-and-health, #national-institutes-of-health

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Treating Mild Coronavirus Cases Could Help Save Everyone

Acting before or very soon after an infection is the best way to handle most acute viral diseases. Why aren’t we focusing on that with Covid-19?

#antibiotics, #antibodies, #chicken-pox, #china, #clinical-trials, #coronavirus-2019-ncov, #deaths-fatalities, #drugs-pharmaceuticals, #hepatitis, #hydroxychloroquine-drug, #immune-system, #influenza, #national-institute-of-allergy-and-infectious-diseases, #national-institutes-of-health, #preventive-medicine, #quarantines, #rabies, #respiratory-diseases, #sars-severe-acute-respiratory-syndrome, #tamiflu-drug, #tests-medical, #trump-donald-j, #wuhan-china

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Prominent Scientists Denounce End to Coronavirus Grant

A group of 77 Nobel laureates wants the U.S. government to review a grant cancellation for research in China directly related to preventing pandemics.

#azar-alex-m-ii, #collins-francis-s, #coronavirus-2019-ncov, #daszak-peter, #ecohealth-alliance, #national-institutes-of-health, #trump-donald-j, #varmus-harold-e, #wuhan-china, #your-feed-science

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What to Expect When a Coronavirus Vaccine Finally Arrives

Sobering lessons from the history of the polio vaccine.

#clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #epidemics, #fauci-anthony-s, #national-institutes-of-health, #poliomyelitis, #salk-jonas-e, #vaccination-and-immunization

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Prototype Vaccines Protect Monkeys From Coronavirus

A series of animal experiments may point the way to an effective human vaccine, scientists said.

#antibodies, #beth-israel-deaconess-medical-center, #boston-mass, #clinical-trials, #coronavirus-2019-ncov, #immune-system, #monkeys-and-apes, #national-institutes-of-health, #science-journal, #vaccination-and-immunization, #your-feed-science

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Arkansas Professor Is Accused of Hiding Chinese Funding

The case was the latest example of the Justice Department’s efforts to combat Chinese influence on American campuses.

#atlanta-ga, #china, #chinese-academy-of-sciences, #colleges-and-universities, #emory-university, #espionage-and-intelligence-services, #fayetteville-ark, #federal-bureau-of-investigation, #justice-department, #national-aeronautics-and-space-administration, #national-institutes-of-health, #research, #tax-evasion, #united-states-politics-and-government, #university-of-arkansas

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We’re All Casualties of Trump’s War on Coronavirus Science

The administration kneecaps experts as the coronavirus rages.

#bright-rick-a, #china, #coronavirus-2019-ncov, #daszak-peter, #ecohealth-alliance, #epidemics, #national-institutes-of-health, #science-and-technology, #trump-donald-j, #united-states-politics-and-government, #vaccination-and-immunization, #whistle-blowers, #wuhan-china

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F.D.A. Orders Companies to Submit Antibody Test Data

The agency had come under fire from members of Congress and other groups for allowing dozens of wildly inaccurate tests to proliferate without oversight.

#antibodies, #coronavirus-2019-ncov, #food-and-drug-administration, #national-institutes-of-health, #quarantines, #tests-medical, #your-feed-healthcare

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How A.I. Steered Doctors Toward a Possible Coronavirus Treatment

Specialists at the London start-up BenevolentAI helped identify the arthritis drug baricitinib, which is now part of a clinical trial.

#artificial-intelligence, #baricitinib, #benevolentai-ltd, #clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #eli-lilly-and-company, #national-institutes-of-health

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Trump’s Response to Virus Reflects a Long Disregard for Science

The president’s Covid-19 response has extended the administration’s longstanding practice of undermining scientific expertise for political purposes.

#centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #environment, #environmental-protection-agency, #global-warming, #greenhouse-gas-emissions, #hydroxychloroquine-drug, #medicine-and-health, #national-institutes-of-health, #regulation-and-deregulation-of-industry, #science-and-technology, #trump-donald-j, #united-states-politics-and-government

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Can Antibody Tests Help End the Coronavirus Pandemic?

The tests are not reliable enough to guide policy on lockdowns and reopenings, experts said. But they can help model the spread of the virus.

#antibodies, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #cuomo-andrew-m, #deaths-fatalities, #epidemics, #hanage-william-p, #los-angeles-calif, #national-institutes-of-health, #new-york-city, #new-york-state, #santa-clara-county-calif, #tests-medical, #world-health-organization, #your-feed-science

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Coronavirus Vaccine Doctor Says He Was Fired Over Doubts on Hydroxychloroquine

Rick Bright was abruptly dismissed this week as the director of the Department of Health and Human Services’ Biomedical Advanced Research and Development Authority.

#biomedical-advanced-research-and-development-authority, #bright-rick-a, #chloroquine-drug, #coronavirus-2019-ncov, #health-and-human-services-department, #hydroxychloroquine-drug, #national-institutes-of-health, #trump-donald-j, #united-states-politics-and-government, #vaccination-and-immunization, #whistle-blowers

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Disposable N95 Masks Can Be Decontaminated, Researchers Confirm

Several methods are effective at killing the new coronavirus on N95 masks — primary protective gear for health care workers — for two or three rounds of use.

#coronavirus-2019-ncov, #hydrogen-peroxide, #kumar-anand, #masks, #munster-vincent, #national-institute-of-allergy-and-infectious-diseases, #national-institutes-of-health, #research, #shortages, #ultraviolet-light, #your-feed-healthcare

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Despite Qualms, Arthritis Drug Is to Be Tested in Coronavirus Study

Even though it can make infections worse, it also may be able to keep the immune system from overreacting.

#clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #eli-lilly-and-company, #national-institute-of-allergy-and-infectious-diseases, #national-institutes-of-health, #remdesivir-drug, #rheumatoid-arthritis, #your-feed-science

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Trump Makes Room for Experts, but Still Takes a Leading Role on Coronavirus

Appearing before cameras sometimes multiple times a day to talk about the outbreak, the president has offered rosy assessments and unproven or even false assertions.

#azar-alex-m-ii, #centers-for-disease-control-and-prevention, #coronavirus-2019-ncov, #fauci-anthony-s, #federal-reserve-system, #national-institutes-of-health, #pence-mike, #presidential-election-of-2020, #trump-donald-j, #united-states-economy, #united-states-politics-and-government, #vaccination-and-immunization

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