The Pasquotank County Sheriff’s Office said that a deputy who was executing a search warrant fatally shot Andrew Brown Jr. in Elizabeth City, N.C. Residents gathered at the scene to demand answers.
The fuel pellet industry is thriving. Supporters see it as a climate-friendly source of rural jobs. For others, it’s a polluter and destroyer of nature.
Kristi Wade credits her husband, Happy Wade, with saving her life when a rabid bobcat attacked her in their North Carolina driveway.
A true story about election fraud.
Like other venture investors over the past year, Cain McClary, co-founder of the investment firm KdT Ventures, recently made the jump to Austin. But unlike the rest of them, he was coming from Black Mountain, NC.
McClary had spent the better part of the last three years with his co-founder Mack Healy building out a portfolio that would be the envy of almost any investor looking at financing startups whose businesses depend on innovations at the borders of current technological achievement.
Since 2017, when the firm closed on the first $3.5 million of what ended up being a $15 million fund (they had targeted $30 million), McClary and Healy managed to find their way onto the cap table of businesses like the green chemicals manufacturer, Solugen; health diagnostics technology developer, PathAI; the Nigerian genetic dataset developer, 54Gene; the novel biomaterials developer, Checkerspot; and the genetics-focused therapy company, Dyno Therapeutics.
That portfolio — and the subsequent top decile performance that Cambridge Associates has said comes with it — has allowed McClary and Healy to close on an oversubscribed $50 million new fund to invest in promising startup companies.
Hailing from a small Tennessee town outside of Leipers Fork (itself a small Tennessee town) McClary studied medicine at Tulane and business at Stanford where he linked up with Healy through a mutual friend.
Healy, who had done stints throughout big Bay Area startups like Airbnb, Databricks, and Facebook brought the software expertise (and some capital to stake the firm) while McClary provided the life sciences know-how.
Together the two men set out to hang their investment shingle at the intersection of software and life sciences that was proving to be fertile ground for new business creation. Each company in the firm’s portfolio depends on both the advances in understanding how to code computers and living cells.
McClary had left California for personal reasons when he launched the fund in 2017 and in 2020 relocated to Austin for professional ones. Healy had already set up shop in the city and it was easier, McClary said to fly out to San Francisco to look for companies from the Austin airport than it was from Ashville.
Also, both men were placing big bets on the Dell Medical School at the University of Texas to become the breeding ground for the type of entrepreneurs that the firm is looking to back.
Mack was there… the Dell Medical School and we think it’s going to be produce the types of entrpereneurs that we want to support. Houston has a med system. I firmly believe that texas has a place at the table in the future
“The way that we define it is that we like to invest in the physical layer of the world,” said McClary. “That includes not only medicine, but chemicals and agriculture. All of that is driven by some of the things that we have this sourcecode for the physical world.”
Mapping the unmapped corners of the frontier tech startup world means that the firm not only has a presence in Austin, but has hired principals to scour Houston and Research Triangle Park in North Carolina for hot deals.
That doesn’t mean the firm is forsaking California though. One of the most recent deals in the KdT portfolio is Andes Ag, an Emeryville, Calif.-based startup that’s applying yield-boosting microbes directly to seeds in an effort to improve crop performance for farmers.
“The KdT team speaks the language of science, making them an outlier in this area of venture investing,” said JD Montgomery of Canterbury Consulting, a limited partner in KdT’s first and second fund. “They are passionate about building the science companies of the future that will tackle some of the significant challenges our world faces in the next decade and beyond.”
In 1966, a Massachusetts mother of three began writing to young men serving in Vietnam. One became her most steadfast pen pal, writing her 77 letters over seven years.
On the Outer Banks, homeowners in Avon are confronting a tax increase of almost 50 percent to protect their homes, the only road into town, and perhaps the community’s very existence.
Kathy Gillcrist said a DNA test she took in 2017 revealed that her father may have been William Bradford Bishop Jr., a fugitive suspected of killing his wife, mother and three sons in 1976.
Antibiotic resistance is one of the biggest potential threats to global health today. But Locus Biosciences is hoping that their crPhage technology might provide a new solution.
Based in North Carolina’s Research Triangle, the startup recently announced promising phase 1b clinical trial results for their use of CRISPR-Cas3-enhanced bacteriophages as a treatment for urinary tract infections caused by escherichia coli. Led in part by former Patheon executive and current Locus CEO Paul Garofolo, the startup launched in 2015 with the goal of using a less popular application of CRISPR technology to address growing antimicrobial resistance.
CRISPR-Cas3 technology has notably different mechanisms from its more well-known CRISPR-Cas9 counterpart. Where the Cas9 enzyme has the ability to cleanly cut through a piece of DNA like a pair of scissors, Garofolo describes Cas3 more like a Pac-Man, shredding the DNA as it moves along a strand.
“You wouldn’t be able to use it for most of the editing platforms people were after,” he said, noting that meant there wouldn’t be as much competition around Cas3. “So I knew it would be protected for some time, and that we could keep it quiet.”
Garofolo and his team wanted to use CRISPR-Cas3 not to edit harmful bacteria found in the body, but to destroy it. To do this, they took the DNA-shredding mechanism of Cas3 and used it to enhance bacteriophages—viruses that can attack and kill different species of bacteria. Together, co-founder and Chief Scientific Officer Dave Ousterout—who has a Ph.D. in biomedical engineering from Duke—thinks this technology offers an extremely direct and targeted way of killing bacteria.
“We armed the phages with this Cas3 system that attacks E. coli, and that sort of dual mechanism of action is what comes together, essentially, as a really potent way to remove just E. coli,” he said in an interview.
That specificity is something that antibiotics lack. Rather than targeting only harmful bacteria in the body, antibiotics typically wipe out all bacteria they come across. “Every time we take antibiotics, we’re not thinking about all the other parts of us that are impacted by the bacteria that do good things,” said Garofolo. But the precision of Locus Biosciences’ crPhage technology means that only the targeted bacteria would be wiped out, leaving those necessary to the body’s normal function intact.
Beyond offering this more specific approach to treatment of pathogens, or any bacteria-based disease, Garofolo and his team also suspect that their approach will also be extremely safe. Though deadly to bacteria, bacteriophages are typically harmless to humans. The safety of CRISPR in humans is well-established, too.
“That’s our secret sauce,” said Garofolo. “We can build drugs that are more powerful than the antibiotics they’re trying to replace, and they use phage, which is probably one of the world’s safest ways to deliver something into the human body.”
While this new technology could certainly help treat pathogens and infectious diseases, Garofolo hopes that indications in immunology, oncology, and neurology might benefit from it too. “We’re starting to figure out that some bacteria might promote cancer, or inflammation in your gut,” he said. If researchers can identify the bacteria at the root cause of those conditions, Garofolo and Ousterout think the crPhage technology might prove to be an effective treatment.
“If we’re right about that, it’s not just about infections or antimicrobial resistance, but helping people overcome cancer or delay the onset of dementia,” Garofolo said. “It’s changing the way we think about how bacteria really help us live.”
Early Stage is the premier ‘how-to’ event for startup entrepreneurs and investors. You’ll hear first-hand how some of the most successful founders and VCs build their businesses, raise money and manage their portfolios. We’ll cover every aspect of company-building: Fundraising, recruiting, sales, product market fit, PR, marketing and brand building. Each session also has audience participation built-in – there’s ample time included for audience questions and discussion.
A video obtained by a TV station appears to show an officer in Salisbury, N.C., hoisting a police dog off the ground by its leash and shoving it into the side of an S.U.V.
She was known for two book series centered on complex female characters, and for stories that illuminated her native North Carolina.
The senator, who is retiring, is one of seven Republicans who voted with Democrats to find Donald J. Trump guilty of inciting an insurrection at the Capitol.
Senator Richard M. Burr’s vote to convict the former president has intensified speculation that Ms. Trump might galvanize staunch Trump loyalists behind a possible bid for Mr. Burr’s seat in 2022.
From the Blue Ridge Mountains to Vermont, new distillers are reviving a drink that vanished during Prohibition, giving it the age and polish of a fine brandy.
Folx Health is leveraging the explosion of virtual care services to offer greater access to healthcare focused on the needs of the LGBTQIA+ community, and has raised $25 million in new funding to help it grow.
It’s part of a revolution in care that’s targeting the needs of specific communities with access to physicians that understand those needs. And it’s all made possible by virtual interactions.
“We have a good sense of the nature of the need and the depth of the pain in the community,” said A.G. Breitenstein, the founder and chief executive of Folx Health. “As a non-binary lesbian and healthcare industry veteran, I have seen and experienced firsthand just how broken the current system is for the queer and trans community,”
Breitenstein said Folx would be using the cash to try and expand to all fifty states and increase the available products and services the healthcare company would look to make available to the queer and trans community.
“Whether it’s HRT, PrEP, sexual health or family creation, health care is essential for us to be who we are. It’s about time we build a platform for ourselves, so Queer and Trans people feel seen, heard, and celebrated,” she said in a statement.
That was one reason why Bessemer Venture Partners leapt at the chance to lead the new financing round for Folx, according to Morgan Cheatham, an investor out of Bessemer’s New York office. The other was the size of the market.
“At a high level, 2% of the population identify as transgender,” said Cheatham. “At that math, when we looked at that, we were able to see a multibillion dollar market opportunity not just to provide [hormone replacement therapy], but to provide a healthcare destination for this community.”
Telescoping out to the opportunity to provide care to the LGBTQ community broadly, when that population represents about 10% to 20% of the population is a “deca-billion opportunity,” said Cheatham.
Breitenstein envisions offering family planning services, broad primary care, and sexual health and wellness care in addition to the hormone therapies that the company currently offers.
Folx joins a cohort of companies tackling health issues specifically for the LGBTQIA+ community which include the mental healthcare service, Violet; Included Health, an employee benefit service; and Plume, which focuses on care for the transgender community.
“We believed in the vision and the approach that she’s taking. She’s building a healthcare experience that is celebratory and dignified rather than one that pathologizing healthcare,” said Cheatham.
For Bessemer and Cheatham, the investment speaks to broader opportunities to identify specific populations that need care tailored to their specific experience. That includes companies like Spora Health and Live Chair Health, which focus on providing healthcare specifically to people of color.
“Our individual identities whether it be socioeconomic status, race, gender… All of these things inform how we interface with the medical industrial complex,” Cheatham said.
Previous investors Define Ventures and Polaris Venture Partners will also participate in the round, which follows quickly on the heels of Folx’s launch from stealth in December 2020.
For its patients, Folx Health is offering Hormone Replacement Therapy (HRT: testosterone or estrogen) with monthly plans starting at $59 a month. Folx Health will also begin releasing its sexual health and wellness offerings starting with Erectile Dysfunction (ED) treatment, soon to be followed by at-home STI Testing and Treatment, all customized for the specifics of Queer and Trans bodies, the company said.
The services will include unlimited on-demand clinical support with at-home lab testing (for most plans) and home-delivered medications (costs may vary based on medication). The company’s services are now available in California, Connecticut, Delaware, Florida, Illinois, Massachusetts, North Carolina, New York, Texas, Virginia, and Washington.
The company is also launching a Folx Library, which will serve as a content hub and resource for Queer and Trans health, written by Folx clinicians and its broader community.
“Our partnership with Folx is a historical moment. It’s challenging to articulate how transformative Folx is for our community. We do so mindful of the brilliant and brave Queer and Trans people who fought for this moment to happen,” said Cheatham in a statement.
The Division of Motor Vehicles said it had received complaints about the specialty plate, which had been issued to members of the Sons of Confederate Veterans.
The names of Lara Trump, Ivanka Trump, Donald Trump Jr. and others have been floated as potential political candidates. Here’s what we know about the chances they could run and their considerations.
Law enforcement officials told the senator that they would not pursue charges over his dumping of hundreds of thousands of dollars of stock after Senate coronavirus briefings early in the pandemic.
Only a few weeks after its SPAC IPO, Porch today announced that it has made four acquisitions, worth a total of $122 million. The most important here is probably the acquisition of Homeowners of America for $100 million, which gets Porch deeper into the home insurance space. In addition, Porch is also acquiring mover marketing and data platform V12 for $22 million, as well as home inspection service Palm-Tech and iRoofing, a SaaS application for roofing contractors. Porch did not disclose the acquisition prices for the latter two companies.
You may still think of Porch as a marketplace for home improvement and repair services — and that’s what it started out as when it launched about seven years ago. Yet while it still offers those services, a couple of years after its 2013 launch, the company pivoted to building what it now calls a “vertical software platform for the home.” Through a number of acquisitions, the Porch Group now includes Porch.com, as well as services like HireAHelper, Inspection Support Network for home inspectors, Kandela for providing services around moving and an insurance broker in the form of the Elite Insurance Group. In some form or another, Porch’s tools are now used — either directly or indirectly — by two-thirds of U.S. homebuyers every month.
As Porch founder and CEO Matt Ehrlichman told me, he had originally planned to take his company public through a traditional IPO. He noted that going the increasingly popular SPAC route, though, allowed him to push his timeline up by a year, which in turn now enables the company to make the acquisitions it announced today.
“In total, we had a $323 million fundraise that allows us now to not only be a public company with public currency, but to be very well capitalized. And picking up that year allows us to be able to go and pursue acquisitions that we think make really good fits for Porch,” Ehrlichman told me. While Porch’s guidance for its 2021 revenue was previously $120 million, it’s now updating that guidance to $170 million based on these acquisitions. That would mean Porch would grow its revenue by about 134% year-over-year between 2020 and 2021.
As the company had previously laid out in its public documents, the plan for 2021 was always to get deeper into insurance. Indeed, as Ehrlichman noted, Porch these days tends to think of itself as a vertical software company that layers insurtech on top of its services in order to be able to create a recurring revenue stream. And because Porch offers such a wide range of services already, its customer acquisition costs are essentially zero for these services.
Porch was already a licensed insurance brokerage. With Homeowners of America, it is acquiring a company that is both an insurance carrier as well as a managing general agent..
“We’re able to capture all of the economic value from the consumer as we help them get insurance set up with their new home and we can really control that experience to delight them. As we wrap all the technology we’ve invested in around that experience we can make it super simple and instant to be able to get the right insurance at the right price for your new home. And because we have all of this data about the home that nobody else has — from the inspection we know if the roof is old, we know if the hot water system is gonna break soon and all the appliances — we know all of this data and so it just gives us a really big advantage in insurance.”
Data, indeed, is what a lot of these acquisitions are about. Because Porch knows so much about so many customers, it is able to provide the companies it acquires with access to relevant data, which in turn helps them offer additional services and make smarter decisions.
Homeowners of America is currently operating in six states (Texas, Arizona, North Carolina, South Carolina, Virginia and Georgia) and licensed in 31. It has a network of more than 800 agencies so far and Porch expects to expand the company’s network and geographic reach in the coming months. “Because we have [customer acquisition cost]-free demand all across the country, one of the opportunities for us is simply just to expand that across the nation,” Ehrlichman explained.
As for V12, Porch’s focus is on that company’s mover marketing and data platform. The acquisition should help it reach its medium-term goal of building a $200 million revenue stream in this area. V12 offers services across multiple verticals, though, including in the automotive space, and will continue to do so. The platform’s overall focus is to help brands identify the right time to reach out to a given consumer — maybe before they decide to buy a new car or move. With Porch’s existing data layered on top of V12’s existing capabilities, the company expects that it will be able to expand these features and it will also allow Porch to not offer mover marketing but what Ehrlichman called “pro-mover” services, as well.
“V12 anchors what we call our marketing software division. A key focus of that is mover marketing. That’s where it’s going to have, long term, tremendous differentiation. But there are a number of other things that they’re working on that are going to have really nice growth vectors, and they’ll continue to push those,” said Ehrlichman.
As for the two smaller acquisitions of iRoofing and Palm-Tech, these are more akin to some of the previous acquisitions the company made in the contractor and inspection verticals. Like with those previous acquisitions, the plan is to help them grow faster, in part through integrating them into the overall Porch group’s family of products.
“Our business is and continues to be highly recurring or reoccurring in nature,” said Porch CFO Marty Heimbigner. “Nearly all of our revenues, including that of these new acquisitions, is consistent and predictable. This repeat revenue is also high margin with less than 20% cost of revenue and is expected to grow more than 30% per year on our platform. So, we believe these deals are highly accretive for our shareholders.”
The team is the first Power Five basketball team to start and stop its season because of the pandemic. The men’s basketball team is expected to continue playing.
Peloton has announced that it intends to acquire Precor, one of the world’s largest suppliers of commercial fitness equipment. You probably recognize the Precor brand name if you’ve ever spent time in a hotel or standalone commercial gym, which is exactly why Peloton making this purchase makes a ton of sense at this particular time for the hot home workout brand.
The Precor acquisition will be made via a deal that’s valued at a total of $420 million, and in addition to expanding its commercial business, this also helps Peloton bring on a lot more manufacturing capability in a time when its order queue for its Tread and Bike hardware is deeper than ever, thanks to the increase in demand resulting from the COVID-19 pandemic. Precor already maintains a significant U.S.-based manufacturing operation, as well as dedicated research and development teams and facilities. In total, Peloton says in a press release that it’ll be adding 625,000 square feet of manufacturing facility in the U.S., between Precor facilities in both Whitsett, North Carolina, and Woodinville, Washington.
While the near-term use of the acquisition, which is set to close in 2021 if it meets all approvals, is to speed up delivery times for customers of existing equipment, long-term this deal sets Peloton up nicely for greater commercial market expansion – once the commercial market returns to growth. While the pandemic has been a clear boon for Peloton’s at-home equipment and fitness subscription service, it’s also been devastating for gym chains and hoteliers, meaning that it’s likely Precor’s primary business was taking a considerable hit over the past few months.
This is the largest deal that Peloton has made thus far, but it’s possible it picked up Precor for a relative bargain; Precor owner Anta Sports was said to have been seeking a potential sale fo the company for around $500 million last November. Peloton will be installing Precor President Rob Barker as GM of Peloton Commercial as part of the new deal, and that should help it accelerate the infiltration of its connected equipment in commercial gyms globally once people feel more comfortable about returning to them safely post-pandemic.
Snow biking near Seattle, winter bird-watching near New York and seven other cold-weather activities near large U.S. cities.
Prosecutors said current or former students were part of an operation that funneled thousands of pounds of marijuana, hundreds of kilograms of cocaine and other drugs to fraternities and colleges campuses.
Mr. Regan, a former air quality specialist at the Environmental Protection Agency, is secretary of North Carolina’s Department of Environmental Quality.
A dispute about the reading of August Wilson’s Pulitzer Prize-winning play in an English class escalated at the mostly white Providence Day School in Charlotte, N.C.
Some areas north and west of the Interstate 95 corridor in New Jersey and Pennsylvania may get more than a foot of snow on Wednesday, the National Weather Service said.
Some Trump allies have suggested that Republican lawmakers should override the will of voters who elected Joe Biden the next president.
Rescuers evacuated 31 people from a campground an hour north of Charlotte, which accounted for at least three of the fatalities, the authorities said.
Though they’re still too close to call, they’re tilting in Biden’s direction for now.
Though they’re still too close to call, there are some indications of which way things might go.
The 25-year-old kept the solidly conservative seat in G.O.P. hands after his race had become unexpectedly competitive when he was accused of sexual misconduct and racism.
Here’s a look at the last major pre-election polls released in five swing states, with an eye toward what they say about the way the broader winds are blowing.
Here’s a look at the last major pre-election polls released in five swing states, with an eye toward what they say about the way the broader winds are blowing.
In most states, control of the state legislature comes with the authority to redraw state and federal electoral maps.
The team, formed in the past few months, is trying to make a mark in the mostly white, mostly male world of competitive fishing.
Joe Biden and Cal Cunningham both led their Republican rivals by three points, a Times/Siena College survey found. Perhaps most notably, 64 percent of respondents said they had already voted.
The election anxieties of Americans across the political spectrum are visible in an alarming place: gun sales figures.
The legislature in this battleground state could flip to Democratic control, a prospect that is bringing out lower-income voters who stayed home in 2016.
Even some people in Gastonia, N.C., are a little perplexed about why the president was holding a rally in a small community that’s already in his camp.
The contest in the purple state could determine which party controls the chamber. And if the stakes weren’t high enough, the battle has suddenly convulsed.
Democrats lead in overall numbers, as well as early voting, but voter registration gains in three critical states have given Republicans a cause for hope.
Short on money and under enormous pressure, many swing states are still trying to shore up a democratic process challenged daily by court cases, new laws and surges in the coronavirus.
A surge in worldwide demand for low-cost laptops has created shipment delays and pitted desperate schools against one another.
President Trump trails Joseph R. Biden Jr. by four points in the latest Times/Siena survey of North Carolina, and Senator Thom Tillis is lagging behind his Democratic challenger in a crucial Senate race.
New York’s Twentyeight Health is taking the wildly telemedicine services for women’s health popularized by companies like Nurx and bringing them to a patient population that previously hadn’t had access.
The mission to provide women who are Medicaid or underinsured should not be deprived of the same kinds of care that patients who have more income security or better healthcare coverage enjoy, according to the company’s founder, Amy Fan.
The mission, and the company’s technology, have managed to convince a slew of investors who have poured $5.1 million in seed funding into the new startup. Third Prime led the round, which included investments from Town Hall Ventures, SteelSky Ventures, Aglaé Ventures, GingerBread Capital, Rucker Park Capital, Predictive VC, and angel investors like Stu Libby, Zoe Barry, and Wan Li Zhu.
“Women who are on Medicaid, who are underinsured or without health insurance often struggle to find access to reproductive health services, and these struggles have only increased with COVID-19 pandemic limiting access to in-person appointments,” said Amy Fan, co-founder of Twentyeight Health, in a statement. “We are fighting for healthcare equity, ensuring that all women, particularly BIPOC women and women from low-income backgrounds, can access high quality, dignified and convenient care.”
To ensure that its catering to underserved communities, the company works with Bottomless Closet, a workforce entry program for women, and the 8 colleges in the City University of New York ecosystem including LaGuardia College, which has 45,000 students with 70% coming from families making less than $30,000 in annual income.
The company’s services are currently available across Florida, Maryland, New York, New Jersey, North Carolina and Pennsylvania and it’s the only telemedicine company focused on contraception services to accept Medicaid.
In another example of how awesome this company is, it’s also working to provide free birth control for women who aren’t able to pay out of pocket and are uninsured through a partnership with Bedsider’s Contraceptive Access Fund. The company also donates 2% of its revenue to Bedsider and the National Institute for Reproductive Health. (Y’all, this company is amaze.)
To sign up for the service, new customers fill out a medical questionnaire online. Once the questionnaire is reviewed by a US board-certified doctor within 24 hours customers can access over 100 FDA-approved brands of birth control pills, patches, rings, shots, and emergency contraception and receive a shipment within three days.
Twentyeight Health provides ongoing care through online audio consultations and doctor follow up messages to discuss issues around updating prescriptions or addressing side effects, the company said.
“Today, low-income women are three times more likely to have an unintended pregnancy than the average woman in the U.S., and nearly one-third of physicians nationwide aren’t accepting new Medicaid patients,” said Bruno Van Tuykom, co-founder of Twentyeight Health, in a statement. “This underscores why offering high-quality reproductive care that is inclusive of people across race, income bracket, or health insurance status is more important than ever.”
Launched in 2018, Twentyeight Health said it would use the new cash to continue to expand its services across the U.S.
A surge in worldwide demand by educators for low-cost laptops has created shipment delays and pitted desperate schools against one another. Districts with deep pockets often win out.
Each one is in a battleground state. Votes from people there will matter a lot — and offer Joe Biden several paths to victory.
The Senate race in North Carolina was engulfed in chaos after the incumbent tested positive for coronavirus and his challenger admitted to exchanging romantic texts with a woman who is not his wife.