People Want an Alzheimer’s Drug. Aducanumab Isn’t the One.

An F.D.A. sign-off for aducanumab would make finding a good treatment harder.

#alzheimers-disease, #brain, #clinical-trials, #drugs-pharmaceuticals, #placebos

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My Teens Are Coronavirus Vaccine Guinea Pigs

A health journalist is getting a front-row seat to one of the most-anticipated pediatric trials in history.

#children-and-childhood, #clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #moderna-inc, #parenting, #placebos, #research, #vaccination-and-immunization

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Is It OK to Enroll in a Covid-19 Vaccine Trial If I Might Drop Out?

The magazine’s Ethicist columnist on the importance of control groups and elderly parents’ risky behavior.

#clinical-trials, #coronavirus-2019-ncov, #coronavirus-risks-and-safety-concerns, #placebos, #vaccination-and-immunization

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Many Trial Volunteers Got Placebo Vaccines. Do They Now Deserve the Real Ones?

Some vaccine experts worry that “unblinding” the trials and giving all of the volunteers vaccines would tarnish the long-term results.

#clinical-trials, #coronavirus-2019-ncov, #new-england-journal-of-medicine, #placebos, #research, #vaccination-and-immunization, #volunteers-and-community-service, #your-feed-healthcare, #your-feed-science

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Are Covid-19 Vaccines Really 95% Effective?

You might assume that 95 out of every 100 people vaccinated will be protected from Covid-19. But that’s not how the math works.

#clinical-trials, #coronavirus-2019-ncov, #health-affairs-journal, #moderna-inc, #pfizer-inc, #placebos, #vaccination-and-immunization, #your-feed-healthcare, #your-feed-science

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The First Covid Vaccine Will Not Make Life Normal Again

Come spring, Americans may have their choice of several so-so coronavirus vaccines — with no way of knowing which one is best.

#clinical-trials, #coronavirus-2019-ncov, #coronavirus-risks-and-safety-concerns, #food-and-drug-administration, #national-institutes-of-health, #placebos, #public-private-sector-cooperation, #research, #united-states-politics-and-government, #vaccination-and-immunization, #your-feed-healthcare, #your-feed-science

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Turmeric May Ease Knee Arthritis

A curcumin extract eased pain, stiffness and physical function in those with osteoarthritis of the knee.

#arthritis, #joints-body-part, #knees, #osteoarthritis, #placebos, #turmeric-spice

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Covering Ebola Didn’t Prepare Me for This: I Volunteered for the Covid-19 Vaccine Trial

George Washington University Hospital invited me to participate in Moderna’s vaccine trial because I am triple-risk: a Black woman, a Type 1 diabetic and asthmatic.

#clinical-trials, #content-type-service, #coronavirus-2019-ncov, #fauci-anthony-s, #george-washington-university, #immune-system, #moderna-inc, #placebos, #rna-ribonucleic-acid, #vaccination-and-immunization

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We Don’t Know Enough About Convalescent Plasma

More than 70,000 Covid-19 patients have received it. We have no idea whether it helps.

#blood, #clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #placebos, #research, #united-states

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Remdesivir Tests for Covid Treatments Enter New Phase

A clinical trial showed that remdesivir helped hospitalized patients. Now researchers are asking whether when the drug is paired with another antiviral drug, patients will recover faster.

#chin-hong-peter, #coronavirus-2019-ncov, #dexamethasone-drug, #gilead-sciences-inc, #immune-system, #interferon-beta-drugs, #national-institute-of-allergy-and-infectious-diseases, #placebos, #remdesivir-drug, #research, #tests-medical, #university-of-california, #your-feed-healthcare

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So You Want to Volunteer in a Coronavirus Vaccine Trial

How do you sign up? Will you get paid? Who will cover the costs if you get sick? Here’s a look at the basics.

#coronavirus-2019-ncov, #immune-system, #placebos, #research, #vaccination-and-immunization

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Cutting Corners for a Coronavirus Vaccine Could Cost Lives

It’s tempting to speed up development in a pandemic, but there are good reasons to stick to scientific standards.

#coalition-for-epidemic-preparedness-innovations, #coronavirus-2019-ncov, #ebola-virus, #epidemics, #guillain-barre-syndrome, #placebos, #quarantines, #swine-influenza, #vaccination-and-immunization

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