W.H.O. Rejects Antiviral Drug Remdesivir as a Covid Treatment

In a review of several trials, the World Health Organization found that Gilead’s drug did not improve survival rates for patients nor did it help them recover.

#academic-and-scientific-journals, #bmj-journal, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #gilead-sciences-inc, #remdesivir-drug, #trump-donald-j, #world-health-organization, #your-feed-healthcare

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World Health Organization Rejects Antiviral Drug Remdesivir as Covid-19 Treatment

In a review of several trials, the World Health Organization found that Gilead’s drug did not improve survival rates for patients nor did it help them recover.

#academic-and-scientific-journals, #bmj-journal, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #gilead-sciences-inc, #remdesivir-drug, #trump-donald-j, #world-health-organization, #your-feed-healthcare

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Does Remdesivir Actually Work Against Covid-19?

The evidence shows only that the drug might be effective. That once wasn’t enough for F.D.A. approval.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #remdesivir-drug

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Gilead’s Covid-19 Drug Is Mediocre. It Will Be a Blockbuster Anyway.

Gilead Sciences said Wednesday that remdesivir, which has been authorized for emergency use since the spring, brought in $873 million in revenues so far this year.

#company-reports, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #remdesivir-drug, #research, #your-feed-science

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F.D.A. Approves Remdesivir as First Drug to Treat Covid-19

The move indicated that the drug had cleared more rigorous hurdles since it was given emergency authorization in May.

#clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #remdesivir-drug

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Antibody Treatments, Though Promising, Will Be in Short Supply

All the weak points of American health care — testing delays, communication breakdowns, inequity — are working against this potential treatment.

#antibodies, #clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #elderly, #eli-lilly-and-company, #food-and-drug-administration, #hospitals, #regeneron-pharmaceuticals-inc, #remdesivir-drug, #your-feed-healthcare, #your-feed-science

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Remdesivir Fails to Prevent Covid-19 Deaths in Huge Trial

Critics said the study, sponsored by the W.H.O., was too poorly conducted to be definitive.

#coronavirus-2019-ncov, #deaths-fatalities, #drugs-pharmaceuticals, #gilead-sciences-inc, #remdesivir-drug, #united-states, #world-health-organization, #your-feed-science

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As Trump Seeks to Project Strength, Doctors Disclose Alarming Episodes

The president made a surprise outing from his hospital bed in an effort to show his improvement, but the murky and shifting narrative of his illness was rewritten again with grim new details.

#contact-tracing-public-health, #coronavirus-2019-ncov, #coronavirus-risks-and-safety-concerns, #dexamethasone-drug, #masks, #presidential-election-of-2020, #remdesivir-drug, #trump-coronavirus-positive-result, #trump-donald-j, #united-states-politics-and-government

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Trump’s Treatment Suggests Severe Covid-19, Medical Experts Say

Many of the measures cited by his doctors are reserved for patients severely affected by the coronavirus.

#coronavirus-2019-ncov, #dexamethasone-drug, #drugs-pharmaceuticals, #hospitals, #oxygen, #presidential-election-of-2020, #regeneron-pharmaceuticals-inc, #remdesivir-drug, #tests-drug-use, #trump-coronavirus-positive-result, #trump-donald-j, #united-states, #your-feed-science

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A Timeline of Trump’s Symptoms and Treatments

What is known so far about what happened in the days leading up to the president’s hospitalization.

#coronavirus-2019-ncov, #dexamethasone-drug, #reed-walter-national-military-medical-center, #remdesivir-drug, #social-media, #timeline, #trump-coronavirus-positive-result, #trump-donald-j, #united-states-politics-and-government

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Against the Coronavirus, Imperfect Measures Do the Most Good

Speed and scale may matter more than absolute effectiveness when it comes to tests, masks, treatments and vaccines.

#clinical-trials, #content-type-service, #coronavirus-2019-ncov, #coronavirus-risks-and-safety-concerns, #deaths-fatalities, #dexamethasone-drug, #disease-rates, #drugs-pharmaceuticals, #food-and-drug-administration, #masks, #protective-clothing-and-gear, #remdesivir-drug, #tests-medical, #united-states, #vaccination-and-immunization

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Trump’s Covid-19 Symptoms Are Said to Be ‘Very Concerning’

The president’s medical team refused to provide critical details and left open the impression that he was known to be sick a day earlier than previously reported, forcing them to backtrack later.

#barrett-amy-coney, #coronavirus-2019-ncov, #masks, #presidential-election-of-2020, #reed-walter-national-military-medical-center, #remdesivir-drug, #republican-party, #trump-coronavirus-positive-result, #trump-donald-j

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Trump’s Covid Treatments Suggest a Serious Condition

Outside experts pointed to the therapies as signs that the president’s health may not be as good as his doctors said. His age, weight and gender put him at high risk.

#antibodies, #clinical-trials, #conley-sean-patrick, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #oxygen, #regeneron-pharmaceuticals-inc, #remdesivir-drug, #trump-coronavirus-positive-result, #trump-donald-j, #walter-reed, #walter-reed-national-military-medical-center, #your-feed-healthcare

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Scientists Report Steroids Can Be Lifesaving for Covid-19 Patients

New data in hand, the W.H.O. recommended that doctors give the drugs to critically ill patients worldwide.

#coronavirus-2019-ncov, #dexamethasone-drug, #immune-system, #jama-journal-of-american-medical-assn, #remdesivir-drug, #steroids, #vanderbilt-university, #world-health-organization, #your-feed-science

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Remdesivir Tests for Covid Treatments Enter New Phase

A clinical trial showed that remdesivir helped hospitalized patients. Now researchers are asking whether when the drug is paired with another antiviral drug, patients will recover faster.

#chin-hong-peter, #coronavirus-2019-ncov, #dexamethasone-drug, #gilead-sciences-inc, #immune-system, #interferon-beta-drugs, #national-institute-of-allergy-and-infectious-diseases, #placebos, #remdesivir-drug, #research, #tests-medical, #university-of-california, #your-feed-healthcare

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How Covid Sends Some Bodies to War With Themselves

Many Covid-19 patients may be dying from their immune response to the virus, not from the virus itself. Can science figure out how to save them?

#coronavirus-2019-ncov, #immune-system, #remdesivir-drug, #research

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Remdesivir Could Be in Short Supply. Here’s a Fix.

The federal government must work to ensure adequate supply of the coronavirus drug — and distribute it evenly and transparently.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #generic-brands-and-products, #gilead-sciences-inc, #health-and-human-services-department, #inventions-and-patents, #massachusetts-general-hospital, #remdesivir-drug, #united-states

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Who Gets the Covid-19 Vaccine First? Here’s One Idea

A weighted lottery gives everyone a chance at a drug or vaccine in short supply. But some have a better shot than others.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #rationing-and-allocation-of-resources, #remdesivir-drug, #shortages, #vaccination-and-immunization

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As Coronavirus Slams Houston Hospitals, It’s Like New York ‘All Over Again’

The death toll is lower, but there are echoes of March as cases spike, doctors fall ill and supplies run short. Now, Texas is trying to adapt hard-won lessons while addressing a new set of challenges.

#abbott-gregory-w-1957, #bellevue-hospital-center, #brooklyn-hospital-center, #coronavirus-2019-ncov, #coronavirus-reopenings, #coronavirus-risks-and-safety-concerns, #dexamethasone-drug, #elmhurst-hospital-center, #hospitals, #houston-tex, #houston-methodist-hospital, #mount-sinai-medical-center, #new-york-city, #remdesivir-drug, #texas

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Why Surviving Covid Might Come Down to Which NYC Hospital Admits You

In New York City’s poor neighborhoods, some patients have languished in understaffed hospitals, with substandard equipment. It was a different story in Manhattan’s private medical centers.

#bronx-nyc, #brooklyn-nyc, #coronavirus-2019-ncov, #deaths-fatalities, #hospitals, #income-inequality, #manhattan-nyc, #new-york-city, #queens-nyc, #remdesivir-drug

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House Votes to Limit Health Costs as Drug Maker Adds Price Tag to Virus Treatment

A Democratic measure would cap insurance costs and grant the government the power to negotiate drug costs just as the coronavirus pandemic renews concerns over prices.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #law-and-legislation, #patient-protection-and-affordable-care-act-2010, #remdesivir-drug, #trump-donald-j, #united-states-politics-and-government

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Gilead to Test a Version of Remdesivir That Can Be Inhaled

As scientists study the effectiveness of the drug against the coronavirus, others are exploring how to make the potential treatment easier to administer.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #northwell-health, #remdesivir-drug, #steroids, #your-feed-health, #your-feed-science

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Remdesivir Coronavirus Trial: Federal Scientists Finally Publish Data

A clinical trial led to the authorization of the only drug shown to work in Covid-19 patients. But until now, few experts had seen the numbers.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #kalil-andre, #national-institute-of-allergy-and-infectious-diseases, #new-england-journal-of-medicine, #remdesivir-drug, #research, #united-states

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How Upbeat Vaccine News Fueled a Stock Surge, and an Uproar

The desperate hunt for treatments and vaccines has changed how researchers, regulators, drug companies like Moderna, investors and journalists do their jobs.

#academic-and-scientific-journals, #biorxiv, #biotechnology-and-bioengineering, #clinical-trials, #coronavirus-2019-ncov, #gilead-sciences-inc, #medrxiv, #moderna-inc, #news-and-news-media, #remdesivir-drug, #research, #science-and-technology, #stocks-and-bonds, #vaccination-and-immunization, #your-feed-healthcare

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Can ‘Team Science’ Yield a Covid-19 Treatment?

In just three months, international researchers working together found 30 already existing drugs that seem to stop the coronavirus from destroying human cells.

#centers-for-disease-control-and-prevention, #clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #laboratories-and-scientific-equipment, #remdesivir-drug, #tests-medical

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Haphazard Rollout of Coronavirus Drug Frustrates Doctors

Remdesivir was shipped to small hospitals even as besieged medical centers were denied access.

#amerisourcebergen-corp, #birx-deborah-l, #clinical-trials, #coronavirus-2019-ncov, #food-and-drug-administration, #gilead-sciences-inc, #hospitals, #infectious-diseases-society-of-america, #mcenany-kayleigh, #national-institute-of-allergy-and-infectious-diseases, #pence-mike, #remdesivir-drug, #trump-donald-j, #united-states, #united-states-politics-and-government

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Global Race for a Coronavirus Vaccine Intensifies

Governments, companies and academic labs are accelerating their efforts amid geopolitical crosscurrents, questions about safety and the challenges of producing enough doses for billions of people.

#caplan-arthur-l, #china, #coronavirus-2019-ncov, #fauci-anthony-s, #food-and-drug-administration, #gates-bill, #gates-bill-and-melinda-foundation, #international-relations, #johnsonjohnson, #moderna-inc, #remdesivir-drug, #trump-donald-j, #united-states-politics-and-government, #vaccination-and-immunization

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How Remdesivir, New Hope for Covid-19 Patients, Was Resurrected

The drug failed as a treatment for hepatitis and Ebola. With federal funding, scientists trained it on the coronavirus.

#colds, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #hepatitis, #influenza, #national-institute-of-allergy-and-infectious-diseases, #remdesivir-drug, #research, #rna-ribonucleic-acid, #sars-severe-acute-respiratory-syndrome, #tests-medical, #trump-donald-j, #united-states, #viruses

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What Do We Know About Coronavirus? There Will Be Mistakes.

Urgency demands patience, because advancement is always a product of missteps.

#acquired-immune-deficiency-syndrome, #coronavirus-2019-ncov, #quarantines, #remdesivir-drug, #tests-medical, #vaccination-and-immunization

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Stocks Are Rising as Economic News Worsens

Trillions in stimulus dollars have convinced Wall Street that the government has its back, and investors are seizing on even glimmers of good news about the pandemic.

#amazon-com-inc, #apple-inc, #chevron-corporation, #commerce-department, #coronavirus-2019-ncov, #coronavirus-aid-relief-and-economic-security-act-2020, #exxon-mobil-corp, #federal-reserve-system, #gross-domestic-product, #interest-rates, #recession-and-depression, #remdesivir-drug, #sp-dow-jones-indices, #standardpoors-500-stock-index, #stimulus-economic, #stocks-and-bonds, #united-states, #united-states-economy

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Gilead Claims ‘Positive Data’ to Come From N.I.H. Trial of Remdesivir

Neither the company nor the institutes discussed the data. Another study reported the drug offered no benefit to severely ill patients.

#coronavirus-2019-ncov, #gilead-sciences-inc, #national-institute-of-allergy-and-infectious-diseases, #remdesivir-drug, #your-feed-science

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The Story of Remdesivir

Just as there are no atheists in foxholes, there should be no big-pharma haters in pandemics.

#coronavirus-2019-ncov, #drugs-pharmaceuticals, #food-and-drug-administration, #gilead-sciences-inc, #remdesivir-drug

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Despite Qualms, Arthritis Drug Is to Be Tested in Coronavirus Study

Even though it can make infections worse, it also may be able to keep the immune system from overreacting.

#clinical-trials, #coronavirus-2019-ncov, #drugs-pharmaceuticals, #eli-lilly-and-company, #national-institute-of-allergy-and-infectious-diseases, #national-institutes-of-health, #remdesivir-drug, #rheumatoid-arthritis, #your-feed-science

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